Aerosolized Intratracheal Inoculation of Recombinant Protective Antigen (rPA) Vaccine Provides Protection Against Inhalational Anthrax in B10.D2-Hc 0 Mice

Anthrax caused by is a fatal zoonotic disease with a high lethality and poor prognosis. Inhalational anthrax is the most severe of the three forms of anthrax. The currently licensed commercial human anthrax vaccines require a complex immunization procedure for efficacy and have side effects that lim...

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Veröffentlicht in:	Frontiers in immunology 2022, Vol.13, p.819089
Hauptverfasser:	Song, Xiaolin, Zhang, Wei, Zhai, Lina, Guo, Jianshu, Zhao, Yue, Zhang, Lili, Hu, Lingfei, Xiong, Xiaolu, Zhou, Dongsheng, Lv, Meng, Yang, Wenhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Animals Anthrax - prevention & control Anthrax Vaccines - immunology Antibodies, Bacterial - blood Antibodies, Neutralizing - blood Antigens, Bacterial - immunology Bacillus anthracis - immunology Bacterial Toxins - immunology Female Immunity, Mucosal Immunoglobulin G - blood Mice Powders Survival Analysis Vaccination - methods Vaccines, Subunit - immunology Vaccines, Synthetic - immunology
Online-Zugang:	Volltext
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