Kaempferol increases intracellular ATP content in C 2 C 12 myotubes under hypoxic conditions by suppressing the HIF-1α stabilization and/or by enhancing the mitochondrial complex IV activity

Kaempferol (KMP) has numerous important biological functions, and we recently showed that it remarkably increased intracellular adenosine triphosphate (ATP) content in C C myotubes under hypoxic conditions. Since intracellular ATP is generated by aerobic energy metabolism or anaerobic glycolysis, hy...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2022-05, Vol.103, p.108949
Hauptverfasser:	Akiyama, Minoru, Mizokami, Tsubasa, Miyamoto, Shingo, Ikeda, Yasutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Hypoxia - metabolism Hypoxia-Inducible Factor 1, alpha Subunit - genetics Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Kaempferols Mitochondria - metabolism Muscle Fibers, Skeletal - metabolism Rats
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