African locus reduces the effect of ApoE ε4 allele in Alzheimer’s disease

Background Strong associations between ApoE ε4 and Alzheimer disease (AD) risk have been confirmed worldwide, but there is variability in the effect size across populations. African (AF)‐descent populations have a lower risk from ApoE ε4 compared to other populations. Studies in admixed populations...

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Veröffentlicht in:Alzheimer's & dementia 2021-12, Vol.17, p.e056210-n/a
Hauptverfasser: Rajabli, Farid, Kunkle, Brian W., Reitz, Christiane, Hendrie, Hugh C, Baiyewu, Olusegun, Ogunniyi, Adesola, Gao, Sujuan, Kushch, Nicholas A., Hamilton‐Nelson, Kara L., Beecham, Gary W., Pericak‐Vance, Margaret A., Vance, Jeffery M.
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Sprache:eng
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