IPCS‐derived APPswe mutant pericytes produce beta‐amyloid and induce the activation of co‐cultured astrocytes

Background The amyloid cascade hypothesis has been the most prevalent theory so far to explain the molecular mechanisms underlying the pathogenesis and progression of Alzheimer’s disease (AD). In parallel, substantial evidence indicates contribution of cerebrovascular dysfunction to development of A...

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Veröffentlicht in:	Alzheimer's & dementia 2021-12, Vol.17, p.e057744-n/a
Hauptverfasser:	Wu, Ying Chieh, Rolova, Taisia, Lehtonen, Šárka, Koistinaho, Jari
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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