De novo PSEN1 mutation (Pro436Gln) in a very early onset posterior variant of Alzheimer’s disease is associated with pyramidal signs

Background Alzheimer’s disease (AD) is a common cause of dementia even in cases with very early onset, and implication of monogenic mutations in the PSEN1, PSEN2, and APP genes must be considered. Strong family history is the rule in autosomal dominant AD associated with mutations in these genes but...

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Veröffentlicht in:	Alzheimer's & dementia 2021-12, Vol.17, p.e052804-n/a
Hauptverfasser:	Agüero, Pablo, Hernández‐Alfonso, Jorge, Sainz, María José, García‐Ribas, Guillermo, Téllez, Raquel, Lorda‐Sánchez, Isabel, Paredes‐Rodríguez, Patricia, Ávila‐Fernández, Almudena, Gomez‐Tortosa, Estrella
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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