Forskolin-induced Organoid Swelling is Associated with Long-term CF Disease Progression

Cystic fibrosis (CF) is a monogenic life-shortening disease associated with highly variable individual disease progression which is difficult to predict. Here we assessed the association of forskolin-induced swelling (FIS) of patient-derived organoids (PDO) with long-term CF disease progression in m...

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Veröffentlicht in:The European respiratory journal 2022-01
Hauptverfasser: Muilwijk, Danya, de Poel, Eyleen, van Mourik, Peter, Suen, Sylvia W F, Vonk, Annelotte M, Brunsveld, Jesse E, Kruisselbrink, Evelien, Oppelaar, Hugo, Hagemeijer, Marne C, Berkers, Gitte, de Winter-de Groot, Karin M, Heida-Michel, Sabine, Jans, Stephan R, van Panhuis, Hannah, van der Eerden, Menno M, van der Meer, Renske, Roukema, Jolt, Dompeling, Edward, Weersink, Els J M, Koppelman, Gerard H, Vries, Robert, Zomer-van Ommen, Domenique D, Eijkemans, Marinus J C, van der Ent, Cornelis K, Beekman, Jeffrey M
Format: Artikel
Sprache:eng
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