Decrease in MAP3Ks expression enhances the cell death caused by hyperthermia

Hyperthermia is a promising anticancer treatment modality. However, the molecular mechanism underlying the thermal sensitivity of tumor cells is largely unknown. The aim of this study was to clarify how biochemical changes triggered by heat stimulate antitumor activity. The expression levels of vari...

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Veröffentlicht in:	International journal of hyperthermia 2022-12, Vol.39 (1), p.200-208
Hauptverfasser:	Enomoto, Atsushi, Fukasawa, Takemichi, Terunuma, Hiroshi, Nakagawa, Keiichi, Yoshizaki, Ayumi, Sato, Shinichi, Miyagawa, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	calcium calpain Cell Death clonogenicity Enzyme Activation HeLa Cells Humans Hyperthermia Hyperthermia, Induced MAP3K Phosphorylation
Online-Zugang:	Volltext
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