Expression of immune-related genes as prognostic biomarkers for the assessment of osteosarcoma clinical outcomes

Cancer immunotherapy is a promising therapeutic approach, but the prognostic value of immune-related genes in osteosarcoma (OS) is unknown. Here, Target-OS RNA-seq data were analyzed to detect differentially expressed genes (DEGs) between OS subgroups, followed by functional enrichment analysis. Cox...

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Veröffentlicht in:	Scientific reports 2021-12, Vol.11 (1), p.24123-24123, Article 24123
Hauptverfasser:	Guo, Junjie, Li, Xiaoyang, Shen, Shen, Wu, Xuejian
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67 631/67/1798 631/67/1857 Adaptor Proteins, Signal Transducing Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Bone cancer Bone Neoplasms - diagnosis Bone Neoplasms - genetics Bone Neoplasms - immunology Bone Neoplasms - mortality Cancer immunotherapy CD79 Antigens CD8 Antigens Complement C1 Complement C2 Exodeoxyribonucleases Female Galanin Genes Humanities and Social Sciences Humans Immunotherapy Male Medical prognosis Membrane Proteins Molecular Targeted Therapy multidisciplinary Multidisciplinary Sciences Osteosarcoma Osteosarcoma - diagnosis Osteosarcoma - genetics Osteosarcoma - immunology Osteosarcoma - mortality Patients Phospholipase D Potassium channels (inwardly-rectifying) Prognosis Receptors, KIR2DL1 Risk Factors Risk groups Sarcoma Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Survival Survival analysis Survival Rate
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