YQFM alleviated cardiac hypertrophy by apoptosis inhibition and autophagy regulation via PI 3 K/AKT/mTOR pathway

As a traditional compound preparation of Chinese medicine, Yiqi Fumai lyophilized injection (YQFM) has protective effects on various cardiac diseases including cardiac hypertrophy, which is the primary cause of arrhythmia. However, the involved mechanism remains unclear. This study was projected to...

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Veröffentlicht in:	Journal of ethnopharmacology 2022-03, Vol.285, p.114835
Hauptverfasser:	Wan, Meixu, Yin, Kunkun, Yuan, Jing, Ma, Shiyan, Xu, Qing, Li, Dekun, Gao, Hui, Gou, Xiangbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Arrhythmias, Cardiac - prevention & control Autophagy - drug effects Cardiomegaly - drug therapy Cardiomegaly - metabolism Cardiomegaly - prevention & control Cardiotonic Agents - pharmacology Drugs, Chinese Herbal - pharmacology Gene Expression Regulation - drug effects Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism Rats Signal Transduction - drug effects TOR Serine-Threonine Kinases - metabolism
Online-Zugang:	Volltext
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