Update on neuroendocrine tumors
Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as the...
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| Veröffentlicht in: | Revista medíca de Chile 2021-06, Vol.149 (6), p.888 |
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| container_title | Revista medíca de Chile |
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| creator | Carrillo, Diego Muñoz-Medel, Matías Retamal, Ignacio Pinto, Mauricio Bravo, María L Nervi, Bruno Peña, José Valenzuela, Yasna Guarda, Francisco J Nilo, Flavia Bello, Fernando Orellana, Pilar Vicentini, Daniel Quintana, Juan Carlos Torres, Paula J Leal, José Luis Garrido, Marcelo |
| description | Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as their capacity for hormone production. Carcinoid syndrome is the most common hormonal syndrome produced by NETs and is characterized by diarrhea, flushing and cardiac valvular lesions. New research brought multiple changes in the classification of these neoplasms and a new understanding about their diagnosis and treatment, promoting a multidisciplinary approach. Somatostatin analogues, radiation, biological, and cytotoxic drugs have improved the prognosis of these patients, which entails a great challenge for healthcare providers. |
| doi_str_mv | 10.4067/s0034-98872021000600888 |
| format | Article |
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The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as their capacity for hormone production. Carcinoid syndrome is the most common hormonal syndrome produced by NETs and is characterized by diarrhea, flushing and cardiac valvular lesions. New research brought multiple changes in the classification of these neoplasms and a new understanding about their diagnosis and treatment, promoting a multidisciplinary approach. 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| fulltext | fulltext |
| identifier | EISSN: 0717-6163 |
| ispartof | Revista medíca de Chile, 2021-06, Vol.149 (6), p.888 |
| issn | 0717-6163 |
| language | spa |
| recordid | cdi_pubmed_primary_34751348 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Antineoplastic Agents - therapeutic use Diarrhea Humans Neuroendocrine Tumors - diagnosis Neuroendocrine Tumors - therapy Somatostatin - therapeutic use |
| title | Update on neuroendocrine tumors |
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