AMP functionalized curdlan nanoparticles as a siRNA carrier: Synthesis, characterization and targeted delivery via adenosine A 2B receptor

Receptor-mediated endocytosis has been used for tissue targeted delivery of short interfering RNA (siRNA) drugs. Herein, we investigated adenosine receptor (AR) as a candidate for receptor-mediated siRNA internalization. We synthesized adenosine functionalized cationic curdlan derivatives (denote Cu...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of biological macromolecules 2021-12, Vol.193 (Pt A), p.866
Hauptverfasser:	Bao, Qingming, Ganbold, Tsogzolmaa, Qiburi, Qiburi, Bao, Mingming, Han, Shuqin, Baigude, Huricha
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Monophosphate - pharmacology Animals beta-Glucans - pharmacology Cell Line, Tumor Humans Mice Nanoparticles Receptor, Adenosine A2B - metabolism RNA, Small Interfering - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!