Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China

Objectives A variety of factors differed between rural and urban areas may further influence iodine status and thyroid structure. Hence, this study compared iodine nutrition, the prevalence of thyroid goiter, and nodules between rural and urban residents in Guangzhou, a southern coastal city of Chin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Endocrine Connections 2021-12, Vol.10 (12), p.1550-1559
Hauptverfasser: Yan, Yuerong, You, Lili, Wang, Xiaoyi, Zhang, Zhuo, Li, Feng, Wu, Hongshi, Wu, Muchao, Zhang, Jin, Wu, Jiayun, Chen, Caixia, Li, Xiaohui, Xia, Biwen, Xu, Mingtong, Yan, Li
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1559
container_issue 12
container_start_page 1550
container_title Endocrine Connections
container_volume 10
creator Yan, Yuerong
You, Lili
Wang, Xiaoyi
Zhang, Zhuo
Li, Feng
Wu, Hongshi
Wu, Muchao
Zhang, Jin
Wu, Jiayun
Chen, Caixia
Li, Xiaohui
Xia, Biwen
Xu, Mingtong
Yan, Li
description Objectives A variety of factors differed between rural and urban areas may further influence iodine status and thyroid structure. Hence, this study compared iodine nutrition, the prevalence of thyroid goiter, and nodules between rural and urban residents in Guangzhou, a southern coastal city of China. Methods A total of 1211 rural residents and 1305 urban residents were enrolled in this cross-sectional study. A questionnaire regarding personal characteristics was administered. Urinary iodine concentration (UIC) was examined. Ultrasonography of the thyroid was performed to evaluate thyroid goiter and nodules. Multiple logistic analysis was used to identify the potential associated factors. Results The median UIC was significantly lower in rural residents than in urban residents (120.80 μg/L vs 136.00 μg/L, P < 0.001). Although the coverage rate of iodized salt was much higher in rural residents than in urban residents (99.59% vs 97.29%, P < 0.001), the percentages of seafood intake (8.60% vs 29.29%, P < 0.001), iodine-containing drug consumption (0.33% vs 1.24%, P = 0.011), and iodine contrast medium injection (0.58% vs 1.87%, P = 0.004) were lower in rural residents than in urban residents. Both the prevalence of thyroid goiters and nodules was significantly higher in rural residents than in urban residents (goiter: 8.06% vs 1.20%, P < 0.001; nodules: 61.89% vs 55.04%, P = 0.023). Living in rural areas was associated with thyroid goiter (OR 5.114, 95% CI 2.893–9.040, P < 0.001). Conclusions There were differences in iodine nutrition and the prevalence of thyroid goiter and nodules in rural and urban residents in Guangzhou. Differentiated and specialized monitoring is recommended in our area.
doi_str_mv 10.1530/EC-21-0418
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_34739389</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_8dea8387f2ad4730a00797ceee1d1cb8</doaj_id><sourcerecordid>2594292467</sourcerecordid><originalsourceid>FETCH-LOGICAL-b485t-b82951cc62d760a3560ec33306cf93aec2eb42d7e8cebf39a7c16ffaa289b7c43</originalsourceid><addsrcrecordid>eNqNkstuEzEUhkcIRKvSDQ-AvETQAV_mYrNAQqNQIlViA2vLY59JXE3s4EtReA1eGCcpUbtBeGP7-Dv_sY__qnpJ8DvSMvx-MdSU1Lgh_El1TnEjataR5umD9Vl1GeMtLoOTjjP8vDpjTc8E4-K8-r30xjpALqdgk_VOzSgmlXK8QmkNaBvgTs3gNCA_lcgueGvQytsEASlnkPMmzxCRdSjkULL3wRxGVfYQrQGX4gekkA4-xjqCPhXJZoem4DfoOiu3-rX2-QoNa-vUi-rZpOYIl_fzRfX98-Lb8KW--Xq9HD7d1GPD21SPnIqWaN1R03dYsbbDoBljuNOTYAo0hbEpZ8A1jBMTqtekmyalKBdjrxt2US2PusarW7kNdqPCTnpl5SHgw0qqkKyeQXIDijPeT1SZ0jusMO5FrwGAGKJHXrQ-HrW2edyA0eXZpRmPRB-fOLuWK38nedcL3vdF4PW9QPA_MsQkNzZqmGflwOcoaSsaKmjT7dE3R_TQ0wDTqQzBcm8KuRgkJXJvigK_enixE_rXAgXgR-AnjH6K2u4_-4QV1_QtoaJr9wbqBlu8UT5w8Nmlkvr2_1MLjY_0aP2BTXayWv3r8n8AX7zmjA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2594292467</pqid></control><display><type>article</type><title>Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Yan, Yuerong ; You, Lili ; Wang, Xiaoyi ; Zhang, Zhuo ; Li, Feng ; Wu, Hongshi ; Wu, Muchao ; Zhang, Jin ; Wu, Jiayun ; Chen, Caixia ; Li, Xiaohui ; Xia, Biwen ; Xu, Mingtong ; Yan, Li</creator><creatorcontrib>Yan, Yuerong ; You, Lili ; Wang, Xiaoyi ; Zhang, Zhuo ; Li, Feng ; Wu, Hongshi ; Wu, Muchao ; Zhang, Jin ; Wu, Jiayun ; Chen, Caixia ; Li, Xiaohui ; Xia, Biwen ; Xu, Mingtong ; Yan, Li</creatorcontrib><description>Objectives A variety of factors differed between rural and urban areas may further influence iodine status and thyroid structure. Hence, this study compared iodine nutrition, the prevalence of thyroid goiter, and nodules between rural and urban residents in Guangzhou, a southern coastal city of China. Methods A total of 1211 rural residents and 1305 urban residents were enrolled in this cross-sectional study. A questionnaire regarding personal characteristics was administered. Urinary iodine concentration (UIC) was examined. Ultrasonography of the thyroid was performed to evaluate thyroid goiter and nodules. Multiple logistic analysis was used to identify the potential associated factors. Results The median UIC was significantly lower in rural residents than in urban residents (120.80 μg/L vs 136.00 μg/L, P &lt; 0.001). Although the coverage rate of iodized salt was much higher in rural residents than in urban residents (99.59% vs 97.29%, P &lt; 0.001), the percentages of seafood intake (8.60% vs 29.29%, P &lt; 0.001), iodine-containing drug consumption (0.33% vs 1.24%, P = 0.011), and iodine contrast medium injection (0.58% vs 1.87%, P = 0.004) were lower in rural residents than in urban residents. Both the prevalence of thyroid goiters and nodules was significantly higher in rural residents than in urban residents (goiter: 8.06% vs 1.20%, P &lt; 0.001; nodules: 61.89% vs 55.04%, P = 0.023). Living in rural areas was associated with thyroid goiter (OR 5.114, 95% CI 2.893–9.040, P &lt; 0.001). Conclusions There were differences in iodine nutrition and the prevalence of thyroid goiter and nodules in rural and urban residents in Guangzhou. Differentiated and specialized monitoring is recommended in our area.</description><identifier>ISSN: 2049-3614</identifier><identifier>EISSN: 2049-3614</identifier><identifier>DOI: 10.1530/EC-21-0418</identifier><identifier>PMID: 34739389</identifier><language>eng</language><publisher>BRISTOL: Bioscientifica Ltd</publisher><subject>Endocrinology &amp; Metabolism ; iodine status ; Life Sciences &amp; Biomedicine ; rural resident ; Science &amp; Technology ; thyroid goiter ; thyroid nodules ; urban resident</subject><ispartof>Endocrine Connections, 2021-12, Vol.10 (12), p.1550-1559</ispartof><rights>The authors</rights><rights>The authors 2021 The authors</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>5</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000751296500006</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-b485t-b82951cc62d760a3560ec33306cf93aec2eb42d7e8cebf39a7c16ffaa289b7c43</citedby><cites>FETCH-LOGICAL-b485t-b82951cc62d760a3560ec33306cf93aec2eb42d7e8cebf39a7c16ffaa289b7c43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679877/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679877/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,2096,2108,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34739389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yan, Yuerong</creatorcontrib><creatorcontrib>You, Lili</creatorcontrib><creatorcontrib>Wang, Xiaoyi</creatorcontrib><creatorcontrib>Zhang, Zhuo</creatorcontrib><creatorcontrib>Li, Feng</creatorcontrib><creatorcontrib>Wu, Hongshi</creatorcontrib><creatorcontrib>Wu, Muchao</creatorcontrib><creatorcontrib>Zhang, Jin</creatorcontrib><creatorcontrib>Wu, Jiayun</creatorcontrib><creatorcontrib>Chen, Caixia</creatorcontrib><creatorcontrib>Li, Xiaohui</creatorcontrib><creatorcontrib>Xia, Biwen</creatorcontrib><creatorcontrib>Xu, Mingtong</creatorcontrib><creatorcontrib>Yan, Li</creatorcontrib><title>Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China</title><title>Endocrine Connections</title><addtitle>ENDOCR CONNECT</addtitle><addtitle>Endocr Connect</addtitle><description>Objectives A variety of factors differed between rural and urban areas may further influence iodine status and thyroid structure. Hence, this study compared iodine nutrition, the prevalence of thyroid goiter, and nodules between rural and urban residents in Guangzhou, a southern coastal city of China. Methods A total of 1211 rural residents and 1305 urban residents were enrolled in this cross-sectional study. A questionnaire regarding personal characteristics was administered. Urinary iodine concentration (UIC) was examined. Ultrasonography of the thyroid was performed to evaluate thyroid goiter and nodules. Multiple logistic analysis was used to identify the potential associated factors. Results The median UIC was significantly lower in rural residents than in urban residents (120.80 μg/L vs 136.00 μg/L, P &lt; 0.001). Although the coverage rate of iodized salt was much higher in rural residents than in urban residents (99.59% vs 97.29%, P &lt; 0.001), the percentages of seafood intake (8.60% vs 29.29%, P &lt; 0.001), iodine-containing drug consumption (0.33% vs 1.24%, P = 0.011), and iodine contrast medium injection (0.58% vs 1.87%, P = 0.004) were lower in rural residents than in urban residents. Both the prevalence of thyroid goiters and nodules was significantly higher in rural residents than in urban residents (goiter: 8.06% vs 1.20%, P &lt; 0.001; nodules: 61.89% vs 55.04%, P = 0.023). Living in rural areas was associated with thyroid goiter (OR 5.114, 95% CI 2.893–9.040, P &lt; 0.001). Conclusions There were differences in iodine nutrition and the prevalence of thyroid goiter and nodules in rural and urban residents in Guangzhou. Differentiated and specialized monitoring is recommended in our area.</description><subject>Endocrinology &amp; Metabolism</subject><subject>iodine status</subject><subject>Life Sciences &amp; Biomedicine</subject><subject>rural resident</subject><subject>Science &amp; Technology</subject><subject>thyroid goiter</subject><subject>thyroid nodules</subject><subject>urban resident</subject><issn>2049-3614</issn><issn>2049-3614</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>DOA</sourceid><recordid>eNqNkstuEzEUhkcIRKvSDQ-AvETQAV_mYrNAQqNQIlViA2vLY59JXE3s4EtReA1eGCcpUbtBeGP7-Dv_sY__qnpJ8DvSMvx-MdSU1Lgh_El1TnEjataR5umD9Vl1GeMtLoOTjjP8vDpjTc8E4-K8-r30xjpALqdgk_VOzSgmlXK8QmkNaBvgTs3gNCA_lcgueGvQytsEASlnkPMmzxCRdSjkULL3wRxGVfYQrQGX4gekkA4-xjqCPhXJZoem4DfoOiu3-rX2-QoNa-vUi-rZpOYIl_fzRfX98-Lb8KW--Xq9HD7d1GPD21SPnIqWaN1R03dYsbbDoBljuNOTYAo0hbEpZ8A1jBMTqtekmyalKBdjrxt2US2PusarW7kNdqPCTnpl5SHgw0qqkKyeQXIDijPeT1SZ0jusMO5FrwGAGKJHXrQ-HrW2edyA0eXZpRmPRB-fOLuWK38nedcL3vdF4PW9QPA_MsQkNzZqmGflwOcoaSsaKmjT7dE3R_TQ0wDTqQzBcm8KuRgkJXJvigK_enixE_rXAgXgR-AnjH6K2u4_-4QV1_QtoaJr9wbqBlu8UT5w8Nmlkvr2_1MLjY_0aP2BTXayWv3r8n8AX7zmjA</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Yan, Yuerong</creator><creator>You, Lili</creator><creator>Wang, Xiaoyi</creator><creator>Zhang, Zhuo</creator><creator>Li, Feng</creator><creator>Wu, Hongshi</creator><creator>Wu, Muchao</creator><creator>Zhang, Jin</creator><creator>Wu, Jiayun</creator><creator>Chen, Caixia</creator><creator>Li, Xiaohui</creator><creator>Xia, Biwen</creator><creator>Xu, Mingtong</creator><creator>Yan, Li</creator><general>Bioscientifica Ltd</general><general>Bioscientifica</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20211201</creationdate><title>Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China</title><author>Yan, Yuerong ; You, Lili ; Wang, Xiaoyi ; Zhang, Zhuo ; Li, Feng ; Wu, Hongshi ; Wu, Muchao ; Zhang, Jin ; Wu, Jiayun ; Chen, Caixia ; Li, Xiaohui ; Xia, Biwen ; Xu, Mingtong ; Yan, Li</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b485t-b82951cc62d760a3560ec33306cf93aec2eb42d7e8cebf39a7c16ffaa289b7c43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Endocrinology &amp; Metabolism</topic><topic>iodine status</topic><topic>Life Sciences &amp; Biomedicine</topic><topic>rural resident</topic><topic>Science &amp; Technology</topic><topic>thyroid goiter</topic><topic>thyroid nodules</topic><topic>urban resident</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yan, Yuerong</creatorcontrib><creatorcontrib>You, Lili</creatorcontrib><creatorcontrib>Wang, Xiaoyi</creatorcontrib><creatorcontrib>Zhang, Zhuo</creatorcontrib><creatorcontrib>Li, Feng</creatorcontrib><creatorcontrib>Wu, Hongshi</creatorcontrib><creatorcontrib>Wu, Muchao</creatorcontrib><creatorcontrib>Zhang, Jin</creatorcontrib><creatorcontrib>Wu, Jiayun</creatorcontrib><creatorcontrib>Chen, Caixia</creatorcontrib><creatorcontrib>Li, Xiaohui</creatorcontrib><creatorcontrib>Xia, Biwen</creatorcontrib><creatorcontrib>Xu, Mingtong</creatorcontrib><creatorcontrib>Yan, Li</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Endocrine Connections</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yan, Yuerong</au><au>You, Lili</au><au>Wang, Xiaoyi</au><au>Zhang, Zhuo</au><au>Li, Feng</au><au>Wu, Hongshi</au><au>Wu, Muchao</au><au>Zhang, Jin</au><au>Wu, Jiayun</au><au>Chen, Caixia</au><au>Li, Xiaohui</au><au>Xia, Biwen</au><au>Xu, Mingtong</au><au>Yan, Li</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China</atitle><jtitle>Endocrine Connections</jtitle><stitle>ENDOCR CONNECT</stitle><addtitle>Endocr Connect</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>10</volume><issue>12</issue><spage>1550</spage><epage>1559</epage><pages>1550-1559</pages><issn>2049-3614</issn><eissn>2049-3614</eissn><abstract>Objectives A variety of factors differed between rural and urban areas may further influence iodine status and thyroid structure. Hence, this study compared iodine nutrition, the prevalence of thyroid goiter, and nodules between rural and urban residents in Guangzhou, a southern coastal city of China. Methods A total of 1211 rural residents and 1305 urban residents were enrolled in this cross-sectional study. A questionnaire regarding personal characteristics was administered. Urinary iodine concentration (UIC) was examined. Ultrasonography of the thyroid was performed to evaluate thyroid goiter and nodules. Multiple logistic analysis was used to identify the potential associated factors. Results The median UIC was significantly lower in rural residents than in urban residents (120.80 μg/L vs 136.00 μg/L, P &lt; 0.001). Although the coverage rate of iodized salt was much higher in rural residents than in urban residents (99.59% vs 97.29%, P &lt; 0.001), the percentages of seafood intake (8.60% vs 29.29%, P &lt; 0.001), iodine-containing drug consumption (0.33% vs 1.24%, P = 0.011), and iodine contrast medium injection (0.58% vs 1.87%, P = 0.004) were lower in rural residents than in urban residents. Both the prevalence of thyroid goiters and nodules was significantly higher in rural residents than in urban residents (goiter: 8.06% vs 1.20%, P &lt; 0.001; nodules: 61.89% vs 55.04%, P = 0.023). Living in rural areas was associated with thyroid goiter (OR 5.114, 95% CI 2.893–9.040, P &lt; 0.001). Conclusions There were differences in iodine nutrition and the prevalence of thyroid goiter and nodules in rural and urban residents in Guangzhou. Differentiated and specialized monitoring is recommended in our area.</abstract><cop>BRISTOL</cop><pub>Bioscientifica Ltd</pub><pmid>34739389</pmid><doi>10.1530/EC-21-0418</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2049-3614
ispartof Endocrine Connections, 2021-12, Vol.10 (12), p.1550-1559
issn 2049-3614
2049-3614
language eng
recordid cdi_pubmed_primary_34739389
source DOAJ Directory of Open Access Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Endocrinology & Metabolism
iodine status
Life Sciences & Biomedicine
rural resident
Science & Technology
thyroid goiter
thyroid nodules
urban resident
title Iodine nutritional status, the prevalence of thyroid goiter and nodules in rural and urban residents: a cross-sectional study from Guangzhou, China
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T11%3A29%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Iodine%20nutritional%20status,%20the%20prevalence%20of%20thyroid%20goiter%20and%20nodules%20in%20rural%20and%20urban%20residents:%20a%20cross-sectional%20study%20from%20Guangzhou,%20China&rft.jtitle=Endocrine%20Connections&rft.au=Yan,%20Yuerong&rft.date=2021-12-01&rft.volume=10&rft.issue=12&rft.spage=1550&rft.epage=1559&rft.pages=1550-1559&rft.issn=2049-3614&rft.eissn=2049-3614&rft_id=info:doi/10.1530/EC-21-0418&rft_dat=%3Cproquest_pubme%3E2594292467%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2594292467&rft_id=info:pmid/34739389&rft_doaj_id=oai_doaj_org_article_8dea8387f2ad4730a00797ceee1d1cb8&rfr_iscdi=true