FUNDAMENTAL AND CLINICAL STUDIES WITH IMIPENEM/CILASTATIN SODIUM, A NEW CARBAPENEM ANTIBIOTIC, IN THE FIELD OF PEDIATRICS

Fundamental and clinical evaluations of imipenem/cilastatin sodium (MK-0787/MK-0791) were carried out in pediatric patients. The following results were obtained: 1. After intravenous drip infusion of single doses of 10mg/10mg/kg to 20mg/20mg/kg of MK-0787/MK-0791 in children, peak plasma levels of M...

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Veröffentlicht in:	Japanese journal of antibiotics 1986/07/25, Vol.39(7), pp.1745-1764
Hauptverfasser:	NAKAZAWA, SUSUMU, SATO, HAJIME, NARITA, AKIRA, MATSUMOTO, KIMIKO, SUZUKI, HIROYUKI, NAKAZAWA, SHINICHI, CHIKAOKA, HIDEJIRO, KOIDO, REIKO, KAMIGAKI, MASATO, NAKADA, YOSHIO, OKA, SHU, NIINO, KENJI
Format:	Artikel
Sprache:	jpn
Schlagworte:	Adolescent Bacterial Infections - drug therapy Child Child, Preschool Cilastatin Cyclopropanes - administration & dosage Cyclopropanes - adverse effects Cyclopropanes - metabolism Drug Combinations Female Humans Imipenem Infant Infusions, Intravenous Kinetics Male Thienamycins - administration & dosage Thienamycins - adverse effects Thienamycins - metabolism
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