How were DTP-related adverse events reduced after the introduction of an acellular pertussis vaccine in Chile?

How were DTP-related adverse events reduced after the introduction of an acellular pertussis vaccine in Chile?

Chile has a passive surveillance system of adverse events following immunization (AEFI) that allows monitoring and evaluating the safety profile of the vaccines administered. Between 2018 and 2019, the National Immunization Program (NIP) changed from a pentavalent whole-cell pertussis vaccine (wP) t...

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Veröffentlicht in:Human vaccines & immunotherapeutics 2021-11, Vol.17 (11), p.4225-4234
Hauptverfasser: Aguirre-Boza, Francisca, San Martín P, Pamela, Valenzuela B, María Teresa
Format: Artikel
Sprache:eng
Schlagworte:
acellular pertussis
adverse events
AEFI
Child, Preschool
Chile - epidemiology
Diphtheria-Tetanus-acellular Pertussis Vaccines - adverse effects
Diphtheria-Tetanus-Pertussis Vaccine - adverse effects
DTaP
hexavalent vaccine
Humans
Infant
Pertussis Vaccine - adverse effects
post-marketing surveillance
Research Paper
Retrospective Studies
spontaneous reporting
vaccine safety
Vaccines, Combined
whole-cell pertussis
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Zusammenfassung:Chile has a passive surveillance system of adverse events following immunization (AEFI) that allows monitoring and evaluating the safety profile of the vaccines administered. Between 2018 and 2019, the National Immunization Program (NIP) changed from a pentavalent whole-cell pertussis vaccine (wP) to a hexavalent (DTaP-IPV-HepB-Hib) acellular pertussis vaccine (aP) for children
ISSN:2164-5515
2164-554X
DOI:10.1080/21645515.2021.1965424