Blind Source Separation in Persistent Atrial Fibrillation Electrocardiograms Using Block-Term Tensor Decomposition With Löwner Constraints
The estimation of the atrial activity (AA) signal from electrocardiogram (ECG) recordings is an important step in the noninvasive analysis of atrial fibrillation (AF), the most common sustained arrhythmia encountered in clinical practice. This problem admits a blind source separation (BSS) formulati...
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description | The estimation of the atrial activity (AA) signal from electrocardiogram (ECG) recordings is an important step in the noninvasive analysis of atrial fibrillation (AF), the most common sustained arrhythmia encountered in clinical practice. This problem admits a blind source separation (BSS) formulation that has been recently posed as a tensor factorization, using the Hankel-based block term decomposition (BTD), which is particularly well-suited to the estimation of exponential models like AA during AF. However, persistent forms of AF are characterized by short R-R intervals and very disorganized (or weak) AA, making it difficult to model AA directly and perform its successful extraction through Hankel-BTD. To overcome this drawback, the present work proposes a tensor approach to estimate QRS complexes and subtract them from the ECG, resulting in a signal that, ideally, only contains the AA component. Such an approach tackles the problem of blind separation of rational functions, which models QRS complexes explicitly. The data tensor admitting a BTD is built from Löwner matrices generated from each lead of the observed ECG. To this end, this paper formulates a variant of the recently proposed constrained alternating group lasso (CAGL) algorithm that imposes Löwner structure on the decomposition blocks. This is done by performing an orthogonal projection, which we explicitly derive, at each iteration of CAGL. Results from experiments with synthetic data show the consistency of the proposed Löwner-constrained AGL (LCAGL) in extracting the desired sources. Experimental results obtained on a population of 20 patients suffering from persistent AF show that the proposed variant outperforms other tensor-based methods in terms of atrial signal estimation quality from ECG records as short as a single heartbeat. |
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M. R. ; Goulart, J. H. de M. ; Fernandes, C. A. R. ; Zarzoso, V.</creator><creatorcontrib>de Oliveira, P. M. R. ; Goulart, J. H. de M. ; Fernandes, C. A. R. ; Zarzoso, V.</creatorcontrib><description>The estimation of the atrial activity (AA) signal from electrocardiogram (ECG) recordings is an important step in the noninvasive analysis of atrial fibrillation (AF), the most common sustained arrhythmia encountered in clinical practice. This problem admits a blind source separation (BSS) formulation that has been recently posed as a tensor factorization, using the Hankel-based block term decomposition (BTD), which is particularly well-suited to the estimation of exponential models like AA during AF. However, persistent forms of AF are characterized by short R-R intervals and very disorganized (or weak) AA, making it difficult to model AA directly and perform its successful extraction through Hankel-BTD. To overcome this drawback, the present work proposes a tensor approach to estimate QRS complexes and subtract them from the ECG, resulting in a signal that, ideally, only contains the AA component. Such an approach tackles the problem of blind separation of rational functions, which models QRS complexes explicitly. The data tensor admitting a BTD is built from Löwner matrices generated from each lead of the observed ECG. To this end, this paper formulates a variant of the recently proposed constrained alternating group lasso (CAGL) algorithm that imposes Löwner structure on the decomposition blocks. This is done by performing an orthogonal projection, which we explicitly derive, at each iteration of CAGL. Results from experiments with synthetic data show the consistency of the proposed Löwner-constrained AGL (LCAGL) in extracting the desired sources. Experimental results obtained on a population of 20 patients suffering from persistent AF show that the proposed variant outperforms other tensor-based methods in terms of atrial signal estimation quality from ECG records as short as a single heartbeat.</description><identifier>ISSN: 2168-2194</identifier><identifier>EISSN: 2168-2208</identifier><identifier>DOI: 10.1109/JBHI.2021.3108699</identifier><identifier>PMID: 34460408</identifier><identifier>CODEN: IJBHA9</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>Algorithms ; Arrhythmia ; Atrial fibrillation ; Atrial Fibrillation - diagnosis ; Bioengineering ; Blind source separation ; block term decomposition ; Cardiac arrhythmia ; Cardiology and cardiovascular system ; Computational modeling ; Computer Science ; constrained alternating group lasso ; Constraints ; Decomposition ; EKG ; electrocardiogram ; Electrocardiography ; Electrocardiography - methods ; Estimation ; Fibrillation ; Heart Atria ; Heart beat ; Human health and pathology ; Humans ; Iterative methods ; Life Sciences ; Löwner matrices ; Mathematical analysis ; Rational functions ; Separation ; Signal and Image Processing ; Signal processing ; Signal Processing, Computer-Assisted ; Signal quality ; Tensors</subject><ispartof>IEEE journal of biomedical and health informatics, 2022-04, Vol.26 (4), p.1538-1548</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2022</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-3331484227f72bbd988e51e24cae1b4524f4ee58a0f221bf6adad8402a97fae23</citedby><cites>FETCH-LOGICAL-c426t-3331484227f72bbd988e51e24cae1b4524f4ee58a0f221bf6adad8402a97fae23</cites><orcidid>0000-0001-9286-1163 ; 0000-0002-9933-9930 ; 0000-0002-5310-4714 ; 0000-0003-1812-6229</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/9525188$$EHTML$$P50$$Gieee$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,792,881,27901,27902,54733</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34460408$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-03326486$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>de Oliveira, P. M. R.</creatorcontrib><creatorcontrib>Goulart, J. H. de M.</creatorcontrib><creatorcontrib>Fernandes, C. A. R.</creatorcontrib><creatorcontrib>Zarzoso, V.</creatorcontrib><title>Blind Source Separation in Persistent Atrial Fibrillation Electrocardiograms Using Block-Term Tensor Decomposition With Löwner Constraints</title><title>IEEE journal of biomedical and health informatics</title><addtitle>JBHI</addtitle><addtitle>IEEE J Biomed Health Inform</addtitle><description>The estimation of the atrial activity (AA) signal from electrocardiogram (ECG) recordings is an important step in the noninvasive analysis of atrial fibrillation (AF), the most common sustained arrhythmia encountered in clinical practice. This problem admits a blind source separation (BSS) formulation that has been recently posed as a tensor factorization, using the Hankel-based block term decomposition (BTD), which is particularly well-suited to the estimation of exponential models like AA during AF. However, persistent forms of AF are characterized by short R-R intervals and very disorganized (or weak) AA, making it difficult to model AA directly and perform its successful extraction through Hankel-BTD. To overcome this drawback, the present work proposes a tensor approach to estimate QRS complexes and subtract them from the ECG, resulting in a signal that, ideally, only contains the AA component. Such an approach tackles the problem of blind separation of rational functions, which models QRS complexes explicitly. The data tensor admitting a BTD is built from Löwner matrices generated from each lead of the observed ECG. To this end, this paper formulates a variant of the recently proposed constrained alternating group lasso (CAGL) algorithm that imposes Löwner structure on the decomposition blocks. This is done by performing an orthogonal projection, which we explicitly derive, at each iteration of CAGL. Results from experiments with synthetic data show the consistency of the proposed Löwner-constrained AGL (LCAGL) in extracting the desired sources. Experimental results obtained on a population of 20 patients suffering from persistent AF show that the proposed variant outperforms other tensor-based methods in terms of atrial signal estimation quality from ECG records as short as a single heartbeat.</description><subject>Algorithms</subject><subject>Arrhythmia</subject><subject>Atrial fibrillation</subject><subject>Atrial Fibrillation - diagnosis</subject><subject>Bioengineering</subject><subject>Blind source separation</subject><subject>block term decomposition</subject><subject>Cardiac arrhythmia</subject><subject>Cardiology and cardiovascular system</subject><subject>Computational modeling</subject><subject>Computer Science</subject><subject>constrained alternating group lasso</subject><subject>Constraints</subject><subject>Decomposition</subject><subject>EKG</subject><subject>electrocardiogram</subject><subject>Electrocardiography</subject><subject>Electrocardiography - methods</subject><subject>Estimation</subject><subject>Fibrillation</subject><subject>Heart Atria</subject><subject>Heart beat</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Iterative methods</subject><subject>Life Sciences</subject><subject>Löwner matrices</subject><subject>Mathematical analysis</subject><subject>Rational functions</subject><subject>Separation</subject><subject>Signal and Image Processing</subject><subject>Signal processing</subject><subject>Signal Processing, Computer-Assisted</subject><subject>Signal quality</subject><subject>Tensors</subject><issn>2168-2194</issn><issn>2168-2208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ESBDL</sourceid><sourceid>RIE</sourceid><sourceid>EIF</sourceid><recordid>eNpdkcFuEzEQhlcIRKvSB0BIyBIXOCTYY6_jPSahJUWRQGoqjpZ3d7Z12bVT2wHxDLwPL8CL4bBpDszFo_H3j2bmL4qXjE4Zo9X7T4vV1RQosClnVMmqelKcApNqAkDV08ecVeKkOI_xnuZQuVTJ58UJF0JSQdVp8WvRW9eSa78LDZJr3JpgkvWOWEe-YIg2JnSJzFOwpieXtg6270fioscmBd-Y0Fp_G8wQyU207pYset98m2wwDGSDLvpAPmDjh62P9p_wq013ZP3n9w-HgSy9iykY61J8UTzrTB_x_PCeFTeXF5vlarL-_PFqOV9PGgEyTTjnTCgBMOtmUNdtpRSWDEE0BlktShCdQCyVoR0AqztpWtMqQcFUs84g8LPi3dj3zvR6G-xgwk_tjdWr-Vrva5RzkELJ7yyzb0d2G_zDDmPSg40N5hs49LuooZSzKg8jeEbf_Ife56u6vIkGWVKoFFcyU2ykmuBjDNgdJ2BU743Ve2P13lh9MDZrXh867-oB26Pi0cYMvBoBi4jH76qEkinF_wIiH6ho</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>de Oliveira, P. M. R.</creator><creator>Goulart, J. H. de M.</creator><creator>Fernandes, C. A. R.</creator><creator>Zarzoso, V.</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</general><general>Institute of Electrical and Electronics Engineers</general><scope>97E</scope><scope>ESBDL</scope><scope>RIA</scope><scope>RIE</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><orcidid>https://orcid.org/0000-0001-9286-1163</orcidid><orcidid>https://orcid.org/0000-0002-9933-9930</orcidid><orcidid>https://orcid.org/0000-0002-5310-4714</orcidid><orcidid>https://orcid.org/0000-0003-1812-6229</orcidid></search><sort><creationdate>20220401</creationdate><title>Blind Source Separation in Persistent Atrial Fibrillation Electrocardiograms Using Block-Term Tensor Decomposition With Löwner Constraints</title><author>de Oliveira, P. M. R. ; Goulart, J. H. de M. ; Fernandes, C. A. R. ; Zarzoso, V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-3331484227f72bbd988e51e24cae1b4524f4ee58a0f221bf6adad8402a97fae23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Algorithms</topic><topic>Arrhythmia</topic><topic>Atrial fibrillation</topic><topic>Atrial Fibrillation - diagnosis</topic><topic>Bioengineering</topic><topic>Blind source separation</topic><topic>block term decomposition</topic><topic>Cardiac arrhythmia</topic><topic>Cardiology and cardiovascular system</topic><topic>Computational modeling</topic><topic>Computer Science</topic><topic>constrained alternating group lasso</topic><topic>Constraints</topic><topic>Decomposition</topic><topic>EKG</topic><topic>electrocardiogram</topic><topic>Electrocardiography</topic><topic>Electrocardiography - methods</topic><topic>Estimation</topic><topic>Fibrillation</topic><topic>Heart Atria</topic><topic>Heart beat</topic><topic>Human health and pathology</topic><topic>Humans</topic><topic>Iterative methods</topic><topic>Life Sciences</topic><topic>Löwner matrices</topic><topic>Mathematical analysis</topic><topic>Rational functions</topic><topic>Separation</topic><topic>Signal and Image Processing</topic><topic>Signal processing</topic><topic>Signal Processing, Computer-Assisted</topic><topic>Signal quality</topic><topic>Tensors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Oliveira, P. 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M. R.</au><au>Goulart, J. H. de M.</au><au>Fernandes, C. A. R.</au><au>Zarzoso, V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blind Source Separation in Persistent Atrial Fibrillation Electrocardiograms Using Block-Term Tensor Decomposition With Löwner Constraints</atitle><jtitle>IEEE journal of biomedical and health informatics</jtitle><stitle>JBHI</stitle><addtitle>IEEE J Biomed Health Inform</addtitle><date>2022-04-01</date><risdate>2022</risdate><volume>26</volume><issue>4</issue><spage>1538</spage><epage>1548</epage><pages>1538-1548</pages><issn>2168-2194</issn><eissn>2168-2208</eissn><coden>IJBHA9</coden><abstract>The estimation of the atrial activity (AA) signal from electrocardiogram (ECG) recordings is an important step in the noninvasive analysis of atrial fibrillation (AF), the most common sustained arrhythmia encountered in clinical practice. This problem admits a blind source separation (BSS) formulation that has been recently posed as a tensor factorization, using the Hankel-based block term decomposition (BTD), which is particularly well-suited to the estimation of exponential models like AA during AF. However, persistent forms of AF are characterized by short R-R intervals and very disorganized (or weak) AA, making it difficult to model AA directly and perform its successful extraction through Hankel-BTD. To overcome this drawback, the present work proposes a tensor approach to estimate QRS complexes and subtract them from the ECG, resulting in a signal that, ideally, only contains the AA component. Such an approach tackles the problem of blind separation of rational functions, which models QRS complexes explicitly. The data tensor admitting a BTD is built from Löwner matrices generated from each lead of the observed ECG. To this end, this paper formulates a variant of the recently proposed constrained alternating group lasso (CAGL) algorithm that imposes Löwner structure on the decomposition blocks. This is done by performing an orthogonal projection, which we explicitly derive, at each iteration of CAGL. Results from experiments with synthetic data show the consistency of the proposed Löwner-constrained AGL (LCAGL) in extracting the desired sources. Experimental results obtained on a population of 20 patients suffering from persistent AF show that the proposed variant outperforms other tensor-based methods in terms of atrial signal estimation quality from ECG records as short as a single heartbeat.</abstract><cop>United States</cop><pub>IEEE</pub><pmid>34460408</pmid><doi>10.1109/JBHI.2021.3108699</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-9286-1163</orcidid><orcidid>https://orcid.org/0000-0002-9933-9930</orcidid><orcidid>https://orcid.org/0000-0002-5310-4714</orcidid><orcidid>https://orcid.org/0000-0003-1812-6229</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Algorithms Arrhythmia Atrial fibrillation Atrial Fibrillation - diagnosis Bioengineering Blind source separation block term decomposition Cardiac arrhythmia Cardiology and cardiovascular system Computational modeling Computer Science constrained alternating group lasso Constraints Decomposition EKG electrocardiogram Electrocardiography Electrocardiography - methods Estimation Fibrillation Heart Atria Heart beat Human health and pathology Humans Iterative methods Life Sciences Löwner matrices Mathematical analysis Rational functions Separation Signal and Image Processing Signal processing Signal Processing, Computer-Assisted Signal quality Tensors |
title | Blind Source Separation in Persistent Atrial Fibrillation Electrocardiograms Using Block-Term Tensor Decomposition With Löwner Constraints |
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