Circular RNA hsa_circ_0000277 sequesters miR-4766-5p to upregulate LAMA1 and promote esophageal carcinoma progression

Growing evidence has indicated that circular RNAs (circRNAs) play a pivotal role as functional RNAs in diverse cancers. However, most circRNAs involved in esophageal squamous cell carcinoma (ESCC) remain undefined, and the underlying molecular mechanisms mediated by circRNAs are largely unclear. Her...

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Veröffentlicht in:	Cell death & disease 2021-07, Vol.12 (7), p.676-676, Article 676
Hauptverfasser:	Zhou, Peng Li, Wu, Zhengyang, Zhang, Wenguang, Xu, Miao, Ren, Jianzhuang, Zhang, Qinhui, Sun, Zhanguo, Han, Xinwei
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/89 38/47 38/61 42/41 631/67/69 631/80/84/2336 64/60 692/53/2422 Animals Antibodies Argonaute 2 protein Biochemistry Bioinformatics Biomedical and Life Sciences Cell Biology Cell Culture Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Circular RNA Disease Progression Epithelial-Mesenchymal Transition Esophageal cancer Esophageal carcinoma Esophageal Neoplasms - genetics Esophageal Neoplasms - metabolism Esophageal Neoplasms - pathology Esophageal Squamous Cell Carcinoma - genetics Esophageal Squamous Cell Carcinoma - metabolism Esophageal Squamous Cell Carcinoma - pathology Esophagus Experiments Gene Expression Regulation, Neoplastic Humans Immunology Immunoprecipitation Laminin Laminin - genetics Laminin - metabolism Life Sciences Male Mesenchyme Metastases Metastasis Mice Mice, Inbred BALB C Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism Molecular modelling Neoplasm Invasiveness Phenotypes Ribonucleic acid RNA RNA, Circular - genetics RNA, Circular - metabolism Signal Transduction Squamous cell carcinoma Tumorigenesis
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