Super‐resolved local recruitment of CLDN5 to filtration slits implicates a direct relationship with podocyte foot process effacement

Under healthy conditions, foot processes of neighbouring podocytes are interdigitating and connected by an electron‐dense slit diaphragm. Besides slit diaphragm proteins, typical adherens junction proteins are also found to be expressed at this cell‐cell junction. It is therefore considered as a hig...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2021-08, Vol.25 (16), p.7631-7641
Hauptverfasser:	Tesch, Florian, Siegerist, Florian, Hay, Eleonora, Artelt, Nadine, Daniel, Christoph, Amann, Kerstin, Zimmermann, Uwe, Kavvadas, Panagiotis, Grisk, Olaf, Chadjichristos, Christos, Endlich, Karlhans, Chatziantoniou, Christos, Endlich, Nicole
Format:	Artikel
Sprache:	eng
Schlagworte:	3D‐structured illumination microscopy Adult Aged Aged, 80 and over Animals Biopsy Claudin-5 - metabolism Claudin‐5 Disease Models, Animal Feet Female Filtration foot process effacement glomerulosclerosis Glomerulosclerosis, Focal Segmental - metabolism Glomerulosclerosis, Focal Segmental - pathology Human health and pathology Humans Kidney diseases Kidney Diseases - metabolism Kidney Diseases - pathology Kidney Glomerulus - metabolism Kidney Glomerulus - pathology Kidneys Lasers Life Sciences Localization Male Membrane Proteins - metabolism Mice Mice, Inbred C57BL Microscopy Middle Aged Nephritis Original podocyte Podocytes - metabolism Podocytes - pathology Proteins Proteinuria Software tight junction proteins Tissues and Organs
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