Gallbladder wall abnormality in biliary atresia of mouse Sox17+/- neonates and human infants

Biliary atresia (BA) is characterized by the inflammation and obstruction of the extrahepatic bile ducts (EHBDs) in newborn infants. SOX17 is a master regulator of the fetal EHBDs formation. In mouse Sox17+/- BA models, SOX17 reduction causes cell-autonomous epithelial shedding together with the ect...

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Veröffentlicht in:Disease models & mechanisms 2020-01
Hauptverfasser: Uemura, Mami, Higashi, Mayumi, Pattarapanawan, Montri, Takami, Shohei, Ichikawa, Naoki, Higashiyama, Hiroki, Furukawa, Taizo, Fujishiro, Jun, Fukumura, Yuki, Yao, Takashi, Tajiri, Tatsuro, Kanai-Azuma, Masami, Kanai, Yoshiakira
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Sprache:eng
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