Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium

Morphogens are important signaling molecules for tissue development and their secretion requires tight regulation. In the wing imaginal disc of flies, the morphogen Wnt/Wingless is apically presented by the secreting cell and re-internalized before final long-range secretion. Why Wnt molecules under...

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Veröffentlicht in:Development (Cambridge) 2020-01
Hauptverfasser: Linnemannstöns, Karen, Witte, Leonie, Karuna, Pradhipa, Kittel, Jeanette, Danieli, Adi, Müller, Denise, Nitsch, Lena, Honemann-Capito, Mona, Grawe, Ferdinand, Wodarz, Andreas, Gross, Julia Christina
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Sprache:eng
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