Increased adriamycin levels in hepatic implants of rabbit Vx-2 carcinoma from regional infusion

Regional infusion chemotherapy for the treatment of primary or secondary hepatic cancer should allow delivery of a higher drug concentration to the tumor with decreased systemic exposure when compared with systemic therapy. Fifteen rabbits, each implanted with two hepatic Vx-2 tumors, were treated w...

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Veröffentlicht in:	Cancer research (Baltimore) 1988-08, Vol.48 (16), p.4584-4587
Hauptverfasser:	RIDGE, J. A, COLLIN, C, BADING, J. R, HANCOCK, C, CONTI, P. S, DALY, J. M, RAAF, J. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Chemotherapy Doxorubicin - administration & dosage Doxorubicin - pharmacokinetics Hepatic Artery Infusions, Intra-Arterial Liver - metabolism Liver Neoplasms, Experimental - drug therapy Liver Neoplasms, Experimental - metabolism Liver Neoplasms, Experimental - pathology Medical sciences Myocardium - metabolism Neoplasm Transplantation Pharmacology. Drug treatments Rabbits Tissue Distribution
Online-Zugang:	Volltext
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