Iron-binding cellular profile of transferrin using label-free Raman hyperspectral imaging and singular value decomposition (SVD)

Serum transferrin (Tf) is the essential iron transport protein in the body. Transferrin is responsible for the sequestration of free iron in serum and the delivery of iron throughout the body and into cells, where iron is released inside a mildly acidified endosome. Altered iron distributions are as...

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Veröffentlicht in:	Free radical biology & medicine 2021-06, Vol.169, p.416-424
Hauptverfasser:	Tubbesing, Kate, Khoo, Ting Chean, Bahreini Jangjoo, Shahab, Sharikova, Anna, Barroso, Margarida, Khmaladze, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry & Molecular Biology Cancer Endocrinology & Metabolism Endosomes - metabolism Hyperspectral Imaging Iron Iron - metabolism Life Sciences & Biomedicine Raman hyperspectral imaging Receptors, Transferrin Redox biology Science & Technology Transferrin
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