Synthesis, Complexation Properties, and Evaluation of New Aminodiphosphonic Acids as Vector Molecules for 68 Ga Radiopharmaceuticals

Two new aminodiphosphonic acids derived from salicylic acid and its phosphonic analogue were prepared through a simple and efficient synthesis. 2-[(2-Amino-2,2-diphosphono)ethyloxy]-benzoic acid and 2-[(2-amino-2,2-diphosphono)ethyloxy]-5-ethyl-phenylphosphonic acid were evaluated for their applicab...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2021-04, Vol.26 (8)
Hauptverfasser:	Maruk, Alesya Ya, Ragulin, Valery V, Mitrofanov, Iurii A, Tsebrikova, Galina S, Solov'ev, Vitaly P, Lunev, Alexandr S, Lunyova, Kristina A, Klementyeva, Olga E, Baulin, Vladimir E, Kodina, Galina E, Tsivadse, Aslan Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chelating Agents - chemical synthesis Chelating Agents - chemistry Chelating Agents - pharmacology Ethylenediamines - chemical synthesis Ethylenediamines - chemistry Ethylenediamines - pharmacology Gallium Radioisotopes - chemistry Gallium Radioisotopes - pharmacology Ligands Magnetic Resonance Spectroscopy Positron-Emission Tomography Radiopharmaceuticals - chemical synthesis Radiopharmaceuticals - chemistry Radiopharmaceuticals - pharmacology Rats
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