The Role of Rotational Motion in Diffusion NMR Experiments on Supramolecular Assemblies: Application to Sup35NM Fibrils

Pulsed‐field gradient (PFG) NMR is an important tool for characterization of biomolecules and supramolecular assemblies. However, for micrometer‐sized objects, such as amyloid fibrils, these experiments become difficult to interpret because in addition to translational diffusion they are also sensit...

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Veröffentlicht in:	Angewandte Chemie International Edition 2021-07, Vol.60 (28), p.15445-15451
Hauptverfasser:	Kharkov, Boris B., Podkorytov, Ivan S., Bondarev, Stanislav A., Belousov, Mikhail V., Salikov, Vladislav A., Zhouravleva, Galina A., Skrynnikov, Nikolai R.
Format:	Artikel
Sprache:	eng
Schlagworte:	amyloid fibrils Amyloidogenesis Assemblies Biomolecules Diffusion Electron microscopy Experiments Fibrils NMR NMR spectroscopy Nuclear magnetic resonance Prion protein proteins Proteolysis pulsed-field gradient diffusion measurements Rotational diffusion Sup35
Online-Zugang:	Volltext
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