Restriction of Cellular Plasticity of Differentiated Cells Mediated by Chromatin Modifiers, Transcription Factors and Protein Kinases

Ectopic expression of master regulatory transcription factors can reprogram the identity of specific cell types. The effectiveness of such induced cellular reprogramming is generally greatly reduced if the cellular substrates are fully differentiated cells. For example, in the nematode C. elegans, t...

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Veröffentlicht in:G3 : genes - genomes - genetics 2019-07, Vol.9 (7), p.2287
Hauptverfasser: Rahe, Dylan P, Hobert, Oliver
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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