Increased Gene Copy Number of DEFA1A3 Is Associated With the Severity of Ulcerative Colitis

DEFA1A3 encodes human neutrophil peptides (HNPs) 1-3 and has multiple copy number variations (CNVs). HNPs are associated with innate immunity. Ulcerative colitis (UC), a chronic inflammatory gastrointestinal disorder, is a life-threatening condition, and predictive markers of UC severity are needed....

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Veröffentlicht in:	Clinical and translational gastroenterology 2021-04, Vol.12 (4), p.e00331-e00331
Hauptverfasser:	Kanmura, Shuji, Morinaga, Yuko, Tanaka, Akihito, Komaki, Yuga, Iwaya, Hiromichi, Kumagai, Kotaro, Mawatari, Seiichi, Sasaki, Fumisato, Tanoue, Shiroh, Hashimoto, Shinichi, Sameshima, Yoichi, Ono, Yohei, Ohi, Hidehisa, Ido, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Inflammatory Bowel Disease
Online-Zugang:	Volltext
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