Inhibitory Effect of Quercetin on Propionibacterium acnes-induced Skin Inflammation

[Display omitted] •Quercetin reduces P. acnes-induced inflammation.•Quercetin have no cytotoxicity in keratinocyte and monocyte.•Quercetin reduces P. acnes-induced pro-inflammatory cytokines expression.•Quercetin reduces P. acnes-induced MAPK phosphorylation.•Quercetin reduces the inflammatory react...

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Veröffentlicht in:	International immunopharmacology 2021-07, Vol.96, p.107557-107557, Article 107557
Hauptverfasser:	Lim, Hyeon-Ji, Kang, Sa-Haeng, Song, Young-Jae, Jeon, Yong-Deok, Jin, Jong-Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Acne Animals Anti-Inflammatory Agents - therapeutic use Antioxidants Cell lines Chemical compounds Cosmetics Cytokines Ear Erythema Flavonoids Gelatinase B Gene Expression Regulation Gram-Positive Bacterial Infections - drug therapy Humans Immunology Inflammation Inflammation - drug therapy Inflammatory diseases Keratinocyte Keratinocytes - physiology Life Sciences & Biomedicine Macrophage Male Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Mice Mice, Inbred BALB C Monocyte mRNA Pharmacology Pharmacology & Pharmacy Phosphorylation Propionibacterium acnes Propionibacterium acnes - physiology Quercetin Quercetin - therapeutic use RAW 264.7 Cells Science & Technology Signal Transduction Skin Skin - immunology Skin diseases Swelling THP-1 Cells TLR2 protein Toll-like receptors
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