Age-related changes in human conventional semen parameters and sperm chromatin structure assay-defined sperm DNA/chromatin integrity

What are the correlations between male age, traditional semen parameters, sperm DNA fragmentation index (DFI) and high DNA stainability (HDS) in a sufficiently large sample size? Retrospective cohort study of 18,441 semen samples, with data divided into seven age groups according to male age: ≤25, 2...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Reproductive biomedicine online 2021-05, Vol.42 (5), p.973-982
Hauptverfasser:	Gao, Jiangman, Yuan, Renpei, Yang, Siwei, Wang, Yuanyuan, Huang, Ying, Yan, Liying, Jiang, Hui, Qiao, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences & Biomedicine Male age Obstetrics & Gynecology Reproductive Biology Science & Technology Semen quality Sperm chromatin structure assay Sperm DNA fragmentation index Sperm high DNA stainability
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	What are the correlations between male age, traditional semen parameters, sperm DNA fragmentation index (DFI) and high DNA stainability (HDS) in a sufficiently large sample size? Retrospective cohort study of 18,441 semen samples, with data divided into seven age groups according to male age: ≤25, 26–30, 31–35, 36–40, 41–45, 46–50 and ≥51 years. Age was negatively correlated with semen volume, total sperm count, motility and HDS, and positively correlated with sperm concentration and DFI (P
ISSN:	1472-6483 1472-6491
DOI:	10.1016/j.rbmo.2021.02.006