Modeling multi-species RNA modification through multi-task curriculum learning

Abstract N6-methyladenosine (m6A) is the most pervasive modification in eukaryotic mRNAs. Numerous biological processes are regulated by this critical post-transcriptional mark, such as gene expression, RNA stability, RNA structure and translation. Recently, various experimental techniques and compu...

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Veröffentlicht in:	Nucleic acids research 2021-04, Vol.49 (7), p.3719-3734
Hauptverfasser:	Xiong, Yuanpeng, He, Xuan, Zhao, Dan, Tian, Tingzhong, Hong, Lixiang, Jiang, Tao, Zeng, Jianyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - chemistry Animals Biochemistry & Molecular Biology Computational Biology Databases, Genetic Datasets as Topic Gene Expression Regulation Humans Life Sciences & Biomedicine Machine Learning RNA - chemistry RNA-Binding Proteins Science & Technology Sequence Analysis, RNA Software Transcriptome
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