Spiramyin-loaded PLGA implants for the treatment of ocular toxoplasmosis: development, characterization, biocompatibility, and anti-toxoplasma activity

Ocular toxoplasmosis is the major cause of infectious posterior uveitis worldwide, inducing visual field defect and/or blindness. Despite the severity of this disease, an effective treatment is still lacking. In this study, spiramycin-loaded PLGA implants were developed aiming at the treatment of oc...

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Veröffentlicht in:	Pharmazie 2021-02, Vol.76 (2), p.68-76
Hauptverfasser:	Tavares, H S, Cardoso, J F, Almeida, T C, Marques, M B F, Mussel, W N, Lopes, M C P, Oréfice, R L, Andrade, S N, Varotti, F P, Silva, G N, Da Silva, G R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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