Higher PGD 2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis

We previously reported that synovial mast cells (MCs) from patients with rheumatoid arthritis (RA) produced TNF-α in response to immune complexes via FcγRI and FcγRIIA. However, the specific functions of synovial MCs in RA remain unclear. This study aimed to elucidate those functions. Synovial tissu...

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Veröffentlicht in:	Scientific reports 2021-03, Vol.11 (1), p.5738
Hauptverfasser:	Mishima, Shintaro, Kashiwakura, Jun-Ichi, Toyoshima, Shota, Sasaki-Sakamoto, Tomomi, Sano, Yutaka, Nakanishi, Kazuyoshi, Matsumoto, Kenji, Okayama, Yoshimichi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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