Serum vasohibin‐1 levels: A potential marker of dermal and pulmonary fibrosis in systemic sclerosis

Vasohibin‐1 (VASH‐1) is a potent anti‐angiogenic factor mainly produced by endothelial cells. In addition, VASH‐1 prevents TGF‐β–dependent activation of renal fibroblasts. Since systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy and fibrosis of multiple organs, VASH‐1 ma...

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Veröffentlicht in:	Experimental dermatology 2021-07, Vol.30 (7), p.951-958
Hauptverfasser:	Fukui, Yuki, Nakamura, Kouki, Hirabayashi, Megumi, Miyagawa, Takuya, Toyama, Satoshi, Omatsu, Jun, Awaji, Kentaro, Ikawa, Tetsuya, Norimatsu, Yuta, Yoshizaki, Ayumi, Sato, Shinichi, Asano, Yoshihide
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angiogenesis Autoimmune diseases Biomarkers - blood Carbon monoxide Cell Cycle Proteins - blood Dermatology Endothelial cells Female Fibroblasts Fibrosis Humans interstitial lung disease KL‐6 Life Sciences & Biomedicine Lung diseases Male Microvasculature Middle Aged mRNA Patients Polymerase Chain Reaction Protein D Pulmonary Fibrosis - diagnosis RNA Science & Technology Scleroderma, Systemic - diagnosis skin sclerosis Surfactant protein D Systemic sclerosis Vascular diseases vasohibin‐1
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