Visible light promoted photoredox C(sp)-H bond functionalization of tetrahydroisoquinolines in flow

A merger of organocatalysis and visible light photoredox catalysis performed in flow allowed access to a wide range of functionalized N -aryl-substituted tetrahydroisoquinolines (THIQs) in a formal C-H oxidation/Mannich reaction. Strecker type functionalization and copper-catalyzed alkynylation of s...

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Veröffentlicht in:	Organic & biomolecular chemistry 2021-03, Vol.19 (12), p.2668-2675
Hauptverfasser:	Filipovi, Ana, D ambaski, Zdravko, Vasiljevi -Radovi, Dana, Bond i, Bojan P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds Catalysis Chemistry Chemistry, Organic Hydrogen bonds Microreactors Oxidation Photoredox catalysis Physical Sciences Science & Technology Substitutes
Online-Zugang:	Volltext
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