Use of Autologous Adipose-Derived Stromal Vascular Fractions in Revision Rhinoplasty for Severe Contractures in Asian Patients
Autologous adipose-derived stromal vascular fraction treatments have been shown to elicit antiinflammatory, antifibrotic, immunomodulatory, angiogenic, and regenerative effects. Injections of adipose-derived stromal vascular fraction have been used to treat severely scarred tissues. Revision septorh...
Gespeichert in:
| Veröffentlicht in: | Plastic and reconstructive surgery (1963) 2021-03, Vol.147 (3), p.401e-411e |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 411e |
|---|---|
| container_issue | 3 |
| container_start_page | 401e |
| container_title | Plastic and reconstructive surgery (1963) |
| container_volume | 147 |
| creator | Ahn, Tae Hwan Lee, Won Kim, Hyoung Moon Cho, Sung Bin Yang, Eun-Jung |
| description | Autologous adipose-derived stromal vascular fraction treatments have been shown to elicit antiinflammatory, antifibrotic, immunomodulatory, angiogenic, and regenerative effects. Injections of adipose-derived stromal vascular fraction have been used to treat severely scarred tissues.
Revision septorhinoplasty was performed in 40 patients with severely contracted noses. Clinical outcomes and adverse events were compared between one group of patients treated with adjuvant adipose-derived stromal vascular fraction injections and a control group of patients treated with adjuvant 0.9% preservative-free saline injections.
In the adipose-derived stromal vascular fraction group, nasal lengths were estimated at 4.2 ± 0.2 cm at baseline to 5.1 ± 0.2 cm at 18 months after revision septorhinoplasty. The lengths of nasal tip projection improved from 2.2 ± 0.2 cm at baseline to 2.9 ± 0.1 cm 18 months after surgery. In addition, nasofrontal angles improved from 125.6 ± 5.1 degrees at baseline to 128.1 ± 4.8 degrees 18 months after surgery. Nasolabial angles in the adipose-derived stromal vascular fraction group were estimated at 105.8 ± 6.5 degrees at baseline and 94.9 ± 5.6 degrees 18 months after surgery. Of these, nasal length, nasal tip projection, and nasolabial angle, but not nasofrontal angle, values improved more in the adipose-derived stromal vascular fraction group than in the control group.
Preoperative and postoperative adjuvant adipose-derived stromal vascular fraction treatment markedly improved the therapeutic outcomes of revision rhinoseptoplasty of severely contracted noses without major side effects.
Therapeutic, III. |
| doi_str_mv | 10.1097/PRS.0000000000007623 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_pubmed_primary_33620926</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2493001850</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3520-5718225d0db71ade096fc67616278b2cdd36bed3f50b31e992a03324fd67484a3</originalsourceid><addsrcrecordid>eNpdkE2P0zAQhi0EYsvCP0DIRy5ZxuPYaY5VYQFpJVYtyzVy4gk1uHGxna72wm_H-8GHGGk0Humd1zMPYy8FnAlomzeXm-0Z_BONRvmILYTCtqqxxsdsASCxEqDwhD1L6RuAaKRWT9mJlBqhRb1gP68S8TDy1ZyDD1_DnPjKukNIVL2l6I5k-TbHsDeefzFpmL2J_DyaIbswJe4mvqGjS6Xhm52bwsGblG_4GCLf0pEi8XWY8q1-jnSnXyVnJn5psqMpp-fsyWh8ohcP9ZRdnb_7vP5QXXx6_3G9uqgGqRAq1YglorJg-0YYS9DqcdCNFhqbZY-DtVL3ZOWooJeC2hYNSIn1aHVTL2sjT9nre99DDD9mSrnbuzSQ92aicnOHdSsLnqWCIq3vpUMMKUUau0N0exNvOgHdLfmukO_-J1_GXj38MPd7sn-GfqP-63sdfKaYvvv5mmK3I-Pz7s5PK1lXCCig7AJVyfL6BYUEjxk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2493001850</pqid></control><display><type>article</type><title>Use of Autologous Adipose-Derived Stromal Vascular Fractions in Revision Rhinoplasty for Severe Contractures in Asian Patients</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Ahn, Tae Hwan ; Lee, Won ; Kim, Hyoung Moon ; Cho, Sung Bin ; Yang, Eun-Jung</creator><creatorcontrib>Ahn, Tae Hwan ; Lee, Won ; Kim, Hyoung Moon ; Cho, Sung Bin ; Yang, Eun-Jung</creatorcontrib><description>Autologous adipose-derived stromal vascular fraction treatments have been shown to elicit antiinflammatory, antifibrotic, immunomodulatory, angiogenic, and regenerative effects. Injections of adipose-derived stromal vascular fraction have been used to treat severely scarred tissues.
Revision septorhinoplasty was performed in 40 patients with severely contracted noses. Clinical outcomes and adverse events were compared between one group of patients treated with adjuvant adipose-derived stromal vascular fraction injections and a control group of patients treated with adjuvant 0.9% preservative-free saline injections.
In the adipose-derived stromal vascular fraction group, nasal lengths were estimated at 4.2 ± 0.2 cm at baseline to 5.1 ± 0.2 cm at 18 months after revision septorhinoplasty. The lengths of nasal tip projection improved from 2.2 ± 0.2 cm at baseline to 2.9 ± 0.1 cm 18 months after surgery. In addition, nasofrontal angles improved from 125.6 ± 5.1 degrees at baseline to 128.1 ± 4.8 degrees 18 months after surgery. Nasolabial angles in the adipose-derived stromal vascular fraction group were estimated at 105.8 ± 6.5 degrees at baseline and 94.9 ± 5.6 degrees 18 months after surgery. Of these, nasal length, nasal tip projection, and nasolabial angle, but not nasofrontal angle, values improved more in the adipose-derived stromal vascular fraction group than in the control group.
Preoperative and postoperative adjuvant adipose-derived stromal vascular fraction treatment markedly improved the therapeutic outcomes of revision rhinoseptoplasty of severely contracted noses without major side effects.
Therapeutic, III.</description><identifier>ISSN: 0032-1052</identifier><identifier>EISSN: 1529-4242</identifier><identifier>DOI: 10.1097/PRS.0000000000007623</identifier><identifier>PMID: 33620926</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Adipose Tissue - blood supply ; Adipose Tissue - cytology ; Adult ; Asians ; Cicatrix - diagnosis ; Cicatrix - etiology ; Cicatrix - surgery ; Combined Modality Therapy - methods ; Contracture - diagnosis ; Contracture - etiology ; Contracture - surgery ; Female ; Humans ; Injections ; Male ; Mesenchymal Stem Cell Transplantation - methods ; Postoperative Complications - diagnosis ; Postoperative Complications - etiology ; Postoperative Complications - surgery ; Reoperation - methods ; Republic of Korea ; Retrospective Studies ; Rhinoplasty - adverse effects ; Rhinoplasty - methods ; Severity of Illness Index ; Treatment Outcome ; Young Adult</subject><ispartof>Plastic and reconstructive surgery (1963), 2021-03, Vol.147 (3), p.401e-411e</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2021 by the American Society of Plastic Surgeons.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3520-5718225d0db71ade096fc67616278b2cdd36bed3f50b31e992a03324fd67484a3</citedby><cites>FETCH-LOGICAL-c3520-5718225d0db71ade096fc67616278b2cdd36bed3f50b31e992a03324fd67484a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33620926$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ahn, Tae Hwan</creatorcontrib><creatorcontrib>Lee, Won</creatorcontrib><creatorcontrib>Kim, Hyoung Moon</creatorcontrib><creatorcontrib>Cho, Sung Bin</creatorcontrib><creatorcontrib>Yang, Eun-Jung</creatorcontrib><title>Use of Autologous Adipose-Derived Stromal Vascular Fractions in Revision Rhinoplasty for Severe Contractures in Asian Patients</title><title>Plastic and reconstructive surgery (1963)</title><addtitle>Plast Reconstr Surg</addtitle><description>Autologous adipose-derived stromal vascular fraction treatments have been shown to elicit antiinflammatory, antifibrotic, immunomodulatory, angiogenic, and regenerative effects. Injections of adipose-derived stromal vascular fraction have been used to treat severely scarred tissues.
Revision septorhinoplasty was performed in 40 patients with severely contracted noses. Clinical outcomes and adverse events were compared between one group of patients treated with adjuvant adipose-derived stromal vascular fraction injections and a control group of patients treated with adjuvant 0.9% preservative-free saline injections.
In the adipose-derived stromal vascular fraction group, nasal lengths were estimated at 4.2 ± 0.2 cm at baseline to 5.1 ± 0.2 cm at 18 months after revision septorhinoplasty. The lengths of nasal tip projection improved from 2.2 ± 0.2 cm at baseline to 2.9 ± 0.1 cm 18 months after surgery. In addition, nasofrontal angles improved from 125.6 ± 5.1 degrees at baseline to 128.1 ± 4.8 degrees 18 months after surgery. Nasolabial angles in the adipose-derived stromal vascular fraction group were estimated at 105.8 ± 6.5 degrees at baseline and 94.9 ± 5.6 degrees 18 months after surgery. Of these, nasal length, nasal tip projection, and nasolabial angle, but not nasofrontal angle, values improved more in the adipose-derived stromal vascular fraction group than in the control group.
Preoperative and postoperative adjuvant adipose-derived stromal vascular fraction treatment markedly improved the therapeutic outcomes of revision rhinoseptoplasty of severely contracted noses without major side effects.
Therapeutic, III.</description><subject>Adipose Tissue - blood supply</subject><subject>Adipose Tissue - cytology</subject><subject>Adult</subject><subject>Asians</subject><subject>Cicatrix - diagnosis</subject><subject>Cicatrix - etiology</subject><subject>Cicatrix - surgery</subject><subject>Combined Modality Therapy - methods</subject><subject>Contracture - diagnosis</subject><subject>Contracture - etiology</subject><subject>Contracture - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Injections</subject><subject>Male</subject><subject>Mesenchymal Stem Cell Transplantation - methods</subject><subject>Postoperative Complications - diagnosis</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - surgery</subject><subject>Reoperation - methods</subject><subject>Republic of Korea</subject><subject>Retrospective Studies</subject><subject>Rhinoplasty - adverse effects</subject><subject>Rhinoplasty - methods</subject><subject>Severity of Illness Index</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0032-1052</issn><issn>1529-4242</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE2P0zAQhi0EYsvCP0DIRy5ZxuPYaY5VYQFpJVYtyzVy4gk1uHGxna72wm_H-8GHGGk0Humd1zMPYy8FnAlomzeXm-0Z_BONRvmILYTCtqqxxsdsASCxEqDwhD1L6RuAaKRWT9mJlBqhRb1gP68S8TDy1ZyDD1_DnPjKukNIVL2l6I5k-TbHsDeefzFpmL2J_DyaIbswJe4mvqGjS6Xhm52bwsGblG_4GCLf0pEi8XWY8q1-jnSnXyVnJn5psqMpp-fsyWh8ohcP9ZRdnb_7vP5QXXx6_3G9uqgGqRAq1YglorJg-0YYS9DqcdCNFhqbZY-DtVL3ZOWooJeC2hYNSIn1aHVTL2sjT9nre99DDD9mSrnbuzSQ92aicnOHdSsLnqWCIq3vpUMMKUUau0N0exNvOgHdLfmukO_-J1_GXj38MPd7sn-GfqP-63sdfKaYvvv5mmK3I-Pz7s5PK1lXCCig7AJVyfL6BYUEjxk</recordid><startdate>20210301</startdate><enddate>20210301</enddate><creator>Ahn, Tae Hwan</creator><creator>Lee, Won</creator><creator>Kim, Hyoung Moon</creator><creator>Cho, Sung Bin</creator><creator>Yang, Eun-Jung</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20210301</creationdate><title>Use of Autologous Adipose-Derived Stromal Vascular Fractions in Revision Rhinoplasty for Severe Contractures in Asian Patients</title><author>Ahn, Tae Hwan ; Lee, Won ; Kim, Hyoung Moon ; Cho, Sung Bin ; Yang, Eun-Jung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3520-5718225d0db71ade096fc67616278b2cdd36bed3f50b31e992a03324fd67484a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adipose Tissue - blood supply</topic><topic>Adipose Tissue - cytology</topic><topic>Adult</topic><topic>Asians</topic><topic>Cicatrix - diagnosis</topic><topic>Cicatrix - etiology</topic><topic>Cicatrix - surgery</topic><topic>Combined Modality Therapy - methods</topic><topic>Contracture - diagnosis</topic><topic>Contracture - etiology</topic><topic>Contracture - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Injections</topic><topic>Male</topic><topic>Mesenchymal Stem Cell Transplantation - methods</topic><topic>Postoperative Complications - diagnosis</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - surgery</topic><topic>Reoperation - methods</topic><topic>Republic of Korea</topic><topic>Retrospective Studies</topic><topic>Rhinoplasty - adverse effects</topic><topic>Rhinoplasty - methods</topic><topic>Severity of Illness Index</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ahn, Tae Hwan</creatorcontrib><creatorcontrib>Lee, Won</creatorcontrib><creatorcontrib>Kim, Hyoung Moon</creatorcontrib><creatorcontrib>Cho, Sung Bin</creatorcontrib><creatorcontrib>Yang, Eun-Jung</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Plastic and reconstructive surgery (1963)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ahn, Tae Hwan</au><au>Lee, Won</au><au>Kim, Hyoung Moon</au><au>Cho, Sung Bin</au><au>Yang, Eun-Jung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of Autologous Adipose-Derived Stromal Vascular Fractions in Revision Rhinoplasty for Severe Contractures in Asian Patients</atitle><jtitle>Plastic and reconstructive surgery (1963)</jtitle><addtitle>Plast Reconstr Surg</addtitle><date>2021-03-01</date><risdate>2021</risdate><volume>147</volume><issue>3</issue><spage>401e</spage><epage>411e</epage><pages>401e-411e</pages><issn>0032-1052</issn><eissn>1529-4242</eissn><abstract>Autologous adipose-derived stromal vascular fraction treatments have been shown to elicit antiinflammatory, antifibrotic, immunomodulatory, angiogenic, and regenerative effects. Injections of adipose-derived stromal vascular fraction have been used to treat severely scarred tissues.
Revision septorhinoplasty was performed in 40 patients with severely contracted noses. Clinical outcomes and adverse events were compared between one group of patients treated with adjuvant adipose-derived stromal vascular fraction injections and a control group of patients treated with adjuvant 0.9% preservative-free saline injections.
In the adipose-derived stromal vascular fraction group, nasal lengths were estimated at 4.2 ± 0.2 cm at baseline to 5.1 ± 0.2 cm at 18 months after revision septorhinoplasty. The lengths of nasal tip projection improved from 2.2 ± 0.2 cm at baseline to 2.9 ± 0.1 cm 18 months after surgery. In addition, nasofrontal angles improved from 125.6 ± 5.1 degrees at baseline to 128.1 ± 4.8 degrees 18 months after surgery. Nasolabial angles in the adipose-derived stromal vascular fraction group were estimated at 105.8 ± 6.5 degrees at baseline and 94.9 ± 5.6 degrees 18 months after surgery. Of these, nasal length, nasal tip projection, and nasolabial angle, but not nasofrontal angle, values improved more in the adipose-derived stromal vascular fraction group than in the control group.
Preoperative and postoperative adjuvant adipose-derived stromal vascular fraction treatment markedly improved the therapeutic outcomes of revision rhinoseptoplasty of severely contracted noses without major side effects.
Therapeutic, III.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>33620926</pmid><doi>10.1097/PRS.0000000000007623</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0032-1052 |
| ispartof | Plastic and reconstructive surgery (1963), 2021-03, Vol.147 (3), p.401e-411e |
| issn | 0032-1052 1529-4242 |
| language | eng |
| recordid | cdi_pubmed_primary_33620926 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adipose Tissue - blood supply Adipose Tissue - cytology Adult Asians Cicatrix - diagnosis Cicatrix - etiology Cicatrix - surgery Combined Modality Therapy - methods Contracture - diagnosis Contracture - etiology Contracture - surgery Female Humans Injections Male Mesenchymal Stem Cell Transplantation - methods Postoperative Complications - diagnosis Postoperative Complications - etiology Postoperative Complications - surgery Reoperation - methods Republic of Korea Retrospective Studies Rhinoplasty - adverse effects Rhinoplasty - methods Severity of Illness Index Treatment Outcome Young Adult |
| title | Use of Autologous Adipose-Derived Stromal Vascular Fractions in Revision Rhinoplasty for Severe Contractures in Asian Patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T20%3A03%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Use%20of%20Autologous%20Adipose-Derived%20Stromal%20Vascular%20Fractions%20in%20Revision%20Rhinoplasty%20for%20Severe%20Contractures%20in%20Asian%20Patients&rft.jtitle=Plastic%20and%20reconstructive%20surgery%20(1963)&rft.au=Ahn,%20Tae%20Hwan&rft.date=2021-03-01&rft.volume=147&rft.issue=3&rft.spage=401e&rft.epage=411e&rft.pages=401e-411e&rft.issn=0032-1052&rft.eissn=1529-4242&rft_id=info:doi/10.1097/PRS.0000000000007623&rft_dat=%3Cproquest_cross%3E2493001850%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2493001850&rft_id=info:pmid/33620926&rfr_iscdi=true |