Metabolomics: small molecules that matter more

Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system. Small molecules, called metabolites or metabolomes with the size of

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecular omics 2021-04, Vol.17 (2), p.21-229
Hauptverfasser: Muthubharathi, Balasubramanian Chellammal, Gowripriya, Thirumugam, Balamurugan, Krishnaswamy
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 229
container_issue 2
container_start_page 21
container_title Molecular omics
container_volume 17
creator Muthubharathi, Balasubramanian Chellammal
Gowripriya, Thirumugam
Balamurugan, Krishnaswamy
description Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system. Small molecules, called metabolites or metabolomes with the size of
doi_str_mv 10.1039/d0mo00176g
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_33598670</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2491065489</sourcerecordid><originalsourceid>FETCH-LOGICAL-c350t-b08c96c7eacccd0ea89023a5749aab43ac4b0da618f14618852761a76eea66bd3</originalsourceid><addsrcrecordid>eNpNkDFPwzAQRi0EolXpwg7KiJBSzrHj2GyoQEFq1QXm6OJcocgmxU4G_j2BlsJyd_ru6RseY6ccJhyEuarBNwC8UC8HbJjlPE8l1_Lw3z1g4xjfoIdMprNMH7OBELnRqoAhmyyoxapxjV_beJ1Ej84lvnFkO0cxaV-xTTy2LYU-DXTCjlboIo13e8Se7--epg_pfDl7nN7MUytyaNMKtDXKFoTW2hoItYFMYF5Ig1hJgVZWUKPiesVlP3WeFYpjoYhQqaoWI3ax7d2E5qOj2JZ-HS05h-_UdLHMpOGgcqlNj15uURuaGAOtyk1YewyfJYfyW1F5C4vlj6JZD5_vervKU71Hf4X0wNkWCNHuv3-OxRf5RmoJ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2491065489</pqid></control><display><type>article</type><title>Metabolomics: small molecules that matter more</title><source>Royal Society Of Chemistry Journals 2008-</source><creator>Muthubharathi, Balasubramanian Chellammal ; Gowripriya, Thirumugam ; Balamurugan, Krishnaswamy</creator><creatorcontrib>Muthubharathi, Balasubramanian Chellammal ; Gowripriya, Thirumugam ; Balamurugan, Krishnaswamy</creatorcontrib><description>Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system. Small molecules, called metabolites or metabolomes with the size of &lt;1500 Da, depict the status of a biological system in a different manner. Currently, we are in need to globally analyze the metabolome and the pathways involved in healthy, as well as diseased conditions, for possible therapeutic applications. Metabolome analysis has revealed high-abundance molecules during different conditions such as diet, environmental stress, microbiota, and disease and treatment states. As a result, it is hard to understand the complete and stable network of metabolites of a biological system. This review helps readers know the available techniques to study metabolomics in addition to other major omics such as genomics, transcriptomics, and proteomics. This review also discusses the metabolomics in various pathological conditions and the importance of metabolomics in therapeutic applications. Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system.</description><identifier>ISSN: 2515-4184</identifier><identifier>EISSN: 2515-4184</identifier><identifier>DOI: 10.1039/d0mo00176g</identifier><identifier>PMID: 33598670</identifier><language>eng</language><publisher>England</publisher><ispartof>Molecular omics, 2021-04, Vol.17 (2), p.21-229</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-b08c96c7eacccd0ea89023a5749aab43ac4b0da618f14618852761a76eea66bd3</citedby><cites>FETCH-LOGICAL-c350t-b08c96c7eacccd0ea89023a5749aab43ac4b0da618f14618852761a76eea66bd3</cites><orcidid>0000-0001-9641-6323 ; 0000-0001-9316-8141</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33598670$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Muthubharathi, Balasubramanian Chellammal</creatorcontrib><creatorcontrib>Gowripriya, Thirumugam</creatorcontrib><creatorcontrib>Balamurugan, Krishnaswamy</creatorcontrib><title>Metabolomics: small molecules that matter more</title><title>Molecular omics</title><addtitle>Mol Omics</addtitle><description>Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system. Small molecules, called metabolites or metabolomes with the size of &lt;1500 Da, depict the status of a biological system in a different manner. Currently, we are in need to globally analyze the metabolome and the pathways involved in healthy, as well as diseased conditions, for possible therapeutic applications. Metabolome analysis has revealed high-abundance molecules during different conditions such as diet, environmental stress, microbiota, and disease and treatment states. As a result, it is hard to understand the complete and stable network of metabolites of a biological system. This review helps readers know the available techniques to study metabolomics in addition to other major omics such as genomics, transcriptomics, and proteomics. This review also discusses the metabolomics in various pathological conditions and the importance of metabolomics in therapeutic applications. Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system.</description><issn>2515-4184</issn><issn>2515-4184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpNkDFPwzAQRi0EolXpwg7KiJBSzrHj2GyoQEFq1QXm6OJcocgmxU4G_j2BlsJyd_ru6RseY6ccJhyEuarBNwC8UC8HbJjlPE8l1_Lw3z1g4xjfoIdMprNMH7OBELnRqoAhmyyoxapxjV_beJ1Ej84lvnFkO0cxaV-xTTy2LYU-DXTCjlboIo13e8Se7--epg_pfDl7nN7MUytyaNMKtDXKFoTW2hoItYFMYF5Ig1hJgVZWUKPiesVlP3WeFYpjoYhQqaoWI3ax7d2E5qOj2JZ-HS05h-_UdLHMpOGgcqlNj15uURuaGAOtyk1YewyfJYfyW1F5C4vlj6JZD5_vervKU71Hf4X0wNkWCNHuv3-OxRf5RmoJ</recordid><startdate>20210401</startdate><enddate>20210401</enddate><creator>Muthubharathi, Balasubramanian Chellammal</creator><creator>Gowripriya, Thirumugam</creator><creator>Balamurugan, Krishnaswamy</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9641-6323</orcidid><orcidid>https://orcid.org/0000-0001-9316-8141</orcidid></search><sort><creationdate>20210401</creationdate><title>Metabolomics: small molecules that matter more</title><author>Muthubharathi, Balasubramanian Chellammal ; Gowripriya, Thirumugam ; Balamurugan, Krishnaswamy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-b08c96c7eacccd0ea89023a5749aab43ac4b0da618f14618852761a76eea66bd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Muthubharathi, Balasubramanian Chellammal</creatorcontrib><creatorcontrib>Gowripriya, Thirumugam</creatorcontrib><creatorcontrib>Balamurugan, Krishnaswamy</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular omics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Muthubharathi, Balasubramanian Chellammal</au><au>Gowripriya, Thirumugam</au><au>Balamurugan, Krishnaswamy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolomics: small molecules that matter more</atitle><jtitle>Molecular omics</jtitle><addtitle>Mol Omics</addtitle><date>2021-04-01</date><risdate>2021</risdate><volume>17</volume><issue>2</issue><spage>21</spage><epage>229</epage><pages>21-229</pages><issn>2515-4184</issn><eissn>2515-4184</eissn><abstract>Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system. Small molecules, called metabolites or metabolomes with the size of &lt;1500 Da, depict the status of a biological system in a different manner. Currently, we are in need to globally analyze the metabolome and the pathways involved in healthy, as well as diseased conditions, for possible therapeutic applications. Metabolome analysis has revealed high-abundance molecules during different conditions such as diet, environmental stress, microbiota, and disease and treatment states. As a result, it is hard to understand the complete and stable network of metabolites of a biological system. This review helps readers know the available techniques to study metabolomics in addition to other major omics such as genomics, transcriptomics, and proteomics. This review also discusses the metabolomics in various pathological conditions and the importance of metabolomics in therapeutic applications. Metabolomics, an analytical study with high-throughput profiling, helps to understand interactions within a biological system.</abstract><cop>England</cop><pmid>33598670</pmid><doi>10.1039/d0mo00176g</doi><tpages>2</tpages><orcidid>https://orcid.org/0000-0001-9641-6323</orcidid><orcidid>https://orcid.org/0000-0001-9316-8141</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 2515-4184
ispartof Molecular omics, 2021-04, Vol.17 (2), p.21-229
issn 2515-4184
2515-4184
language eng
recordid cdi_pubmed_primary_33598670
source Royal Society Of Chemistry Journals 2008-
title Metabolomics: small molecules that matter more
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T06%3A17%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Metabolomics:%20small%20molecules%20that%20matter%20more&rft.jtitle=Molecular%20omics&rft.au=Muthubharathi,%20Balasubramanian%20Chellammal&rft.date=2021-04-01&rft.volume=17&rft.issue=2&rft.spage=21&rft.epage=229&rft.pages=21-229&rft.issn=2515-4184&rft.eissn=2515-4184&rft_id=info:doi/10.1039/d0mo00176g&rft_dat=%3Cproquest_pubme%3E2491065489%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2491065489&rft_id=info:pmid/33598670&rfr_iscdi=true