Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells

Macrophage autophagy is a highly anti-atherogenic process that promotes the catabolism of cytosolic lipid droplets (LDs) to maintain cellular lipid homeostasis. Selective autophagy relies on tags such as ubiquitin and a set of selectivity factors including selective autophagy receptors (SARs) to lab...

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Veröffentlicht in:	Autophagy 2021-11, Vol.17 (11), p.3671-3689
Hauptverfasser:	Robichaud, Sabrina, Fairman, Garrett, Vijithakumar, Viyashini, Mak, Esther, Cook, David P., Pelletier, Alexander R., Huard, Sylvain, Vanderhyden, Barbara C., Figeys, Daniel, Lavallée-Adam, Mathieu, Baetz, Kristin, Ouimet, Mireille
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy cholesterol efflux lipid droplet lipolysis lipophagy macrophage foam cell Research Paper
Online-Zugang:	Volltext
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