The effects of Nigella sativa seeds and thymoquinone on aflatoxin phase-2 detoxification through glutathione and glutathione-S-transferase alpha-3, and the relationship between aflatoxin B 1 -DNA adducts in broilers

The primary pathway of the detoxification of aflatoxin (AF) metabolites occurring at the end of phase-1 biotransformation is glutathione (GSH) conjugation via glutathione-S-transferase (GST) enzyme in phase-2. In this study, the activity of Nigella sativa seeds (NS) and thymoquinone (TQ) on phase-2...

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Veröffentlicht in:	Toxicon (Oxford) 2021-04, Vol.193, p.86
Hauptverfasser:	Ates, Mehmet Burak, Ortatatli, Mustafa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aflatoxin B1 - toxicity Aflatoxins Animals Benzoquinones Chickens - microbiology DNA Adducts Glutathione Glutathione Transferase - metabolism Liver Nigella sativa Seeds
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