Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Skin aging is driven by intrinsic and extrinsic factors impacting on skin functionality with progressive age. One factor of this multifaceted process is cellular senescence, as it has recently been identified to contribute to a declining tissue functionality in old age. In the skin, senescent cells...

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Veröffentlicht in:npj aging and mechanisms of disease 2020-03, Vol.6 (1), p.4
Hauptverfasser: Weinmüllner, Regina, Zbiral, Barbara, Becirovic, Adnan, Stelzer, Elena Maria, Nagelreiter, Fabian, Schosserer, Markus, Lämmermann, Ingo, Liendl, Lisa, Lang, Magdalena, Terlecki-Zaniewicz, Lucia, Andriotis, Orestis, Mildner, Michael, Golabi, Bahar, Waidhofer-Söllner, Petra, Schedle, Karl, Emsenhuber, Gerhard, Thurner, Philipp J, Tschachler, Erwin, Gruber, Florian, Grillari, Johannes
Format: Artikel
Sprache:eng
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