Impact of Implementing CYP2C19 Genotype-Guided Antiplatelet Therapy on P2Y 12 Inhibitor Selection and Clinical Outcomes in Acute Coronary Syndrome Patients After Percutaneous Coronary Intervention: A Real-World Study in China

CYP2C19 loss-of-function (LOF) alleles reduce the effectiveness of clopidogrel in patients undergoing percutaneous coronary intervention for acute coronary syndrome. However, the clinical impact of implementing CYP2C19 gene-guided pharmacotherapy is unclear, especially among the Chinese population....

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Veröffentlicht in:	Frontiers in pharmacology 2020, Vol.11, p.582929
Hauptverfasser:	Zhang, Yi, Shi, Xiu-Jin, Peng, Wen-Xing, Han, Jia-Lun, Lin, Bai-Di, Zhang, Ru, Zhang, Yun-Nan, Yan, Jia-Lin, Wei, Juan-Juan, Wang, Yi-Fan, Chen, Su-Wei, Nan, Nan, Fang, Zhen-Wei, Zeng, Yong, Lin, Yang
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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