α-Particle-induced DNA damage tracks in peripheral blood mononuclear cells of [ 223 Ra]RaCl 2 -treated prostate cancer patients

One therapy option for prostate cancer patients with bone metastases is the use of [ Ra]RaCl . The α-emitter Ra creates DNA damage tracks along α-particle trajectories (α-tracks) in exposed cells that can be revealed by immunofluorescent staining of γ-H2AX+53BP1 DNA double-strand break markers. We i...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2021-02
Hauptverfasser:	Schumann, S, Eberlein, U, Lapa, C, Müller, J, Serfling, S, Lassmann, M, Scherthan, H
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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