Ethambutol Optic Neuropathy: Vigilance and Screening, the Keys to Prevent Blindness with the Revised Anti-tuberculous Therapy Regimen

There has been change in the guidelines for the management of tuberculosis in India. The new guidelines advocate the daily use of Ethambutol for both intensive and continuation phase of the treatment. This may be a matter of concern as increased cumulative dose may lead to increase in incidence of t...

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Veröffentlicht in:Journal of the Association of Physicians of India 2021-02, Vol.69 (2), p.54
Hauptverfasser: Saxena, Rohit, Phuljhele, Swati, Prakash, Anupam, Lodha, Rakesh, Singh, Digvijay, Karna, Satya, Mohan, Anant, Gandhi, Rashmin, Menon, Vimla, Garg, Rajiv, The Inosrg
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container_issue 2
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container_title Journal of the Association of Physicians of India
container_volume 69
creator Saxena, Rohit
Phuljhele, Swati
Prakash, Anupam
Lodha, Rakesh
Singh, Digvijay
Karna, Satya
Mohan, Anant
Gandhi, Rashmin
Menon, Vimla
Garg, Rajiv
The Inosrg
description There has been change in the guidelines for the management of tuberculosis in India. The new guidelines advocate the daily use of Ethambutol for both intensive and continuation phase of the treatment. This may be a matter of concern as increased cumulative dose may lead to increase in incidence of toxic optic neuropathy due to ethambutol. Indian Neuro-Ophthalmology Society has taken cognizance of the issue and has come-up with guidelines for prevention and early detection of the toxic optic neuropathy.
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subjects Antitubercular Agents - adverse effects
Blindness
Ethambutol - adverse effects
Humans
India - epidemiology
Optic Nerve Diseases - chemically induced
Optic Nerve Diseases - diagnosis
Optic Nerve Diseases - prevention & control
Tuberculosis - drug therapy
title Ethambutol Optic Neuropathy: Vigilance and Screening, the Keys to Prevent Blindness with the Revised Anti-tuberculous Therapy Regimen
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