Identification of RNA-binding proteins that partner with Lin28a to regulate Dnmt3a expression

Lin28 is an evolutionary conserved RNA-binding protein that plays important roles during embryonic development and tumorigenesis. It regulates gene expression through two different post-transcriptional mechanisms. The first one is based on the regulation of miRNA biogenesis, in particular that of th...

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Veröffentlicht in:	Scientific reports 2021-01, Vol.11 (1), p.2345-2345, Article 2345
Hauptverfasser:	Parisi, Silvia, Castaldo, Daniela, Piscitelli, Silvia, D’Ambrosio, Chiara, Divisato, Giuseppina, Passaro, Fabiana, Avolio, Rosario, Castellucci, Alessia, Gianfico, Paolo, Masullo, Mariorosario, Scaloni, Andrea, Russo, Tommaso
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337 631/45 631/532 631/80 DNA methyltransferase Embryo cells Embryogenesis Embryonic growth stage Evolutionary conservation Gene expression Humanities and Social Sciences miRNA Molecular weight multidisciplinary Post-transcription Proteins Proteomics RNA-binding protein Science Science (multidisciplinary) Stem cell transplantation Stem cells Tumorigenesis
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