Sox9 EGFP Defines Biliary Epithelial Heterogeneity Downstream of Yap Activity

Defining the genetic heterogeneity of intrahepatic biliary epithelial cells (BECs) is challenging, and tools for identifying BEC subpopulations are limited. Here, we characterize the expression of a Sox9 transgene in the liver and demonstrate that green fluorescent protein (GFP) expression levels ar...

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Veröffentlicht in:	Cellular and molecular gastroenterology and hepatology 2021, Vol.11 (5), p.1437
Hauptverfasser:	Tulasi, Deepthi Y, Castaneda, Diego Martinez, Wager, Kortney, Hogan, Connor B, Alcedo, Karel P, Raab, Jesse R, Gracz, Adam D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile Ducts, Intrahepatic - cytology Bile Ducts, Intrahepatic - metabolism Cell Proliferation Epithelial Cells - cytology Epithelial Cells - metabolism Female Gene Expression Profiling Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Hepatocytes - cytology Hepatocytes - metabolism Male Mice Mice, Inbred C57BL Mice, Transgenic Signal Transduction SOX9 Transcription Factor - genetics SOX9 Transcription Factor - metabolism YAP-Signaling Proteins - genetics YAP-Signaling Proteins - metabolism
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