Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study
Background: Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-1...
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creator | Carrier, Francois Martin Amzallag, Eva Lecluyse, Vincent Cote, Genevieve Couture, Etienne J. D'Aragon, Frederick Kandelman, Stanislas Turgeon, Alexis F. Deschamps, Alain Nitulescu, Roy Djade, Codjo Djignefa Girard, Martin Beaulieu, Pierre Richebe, Philippe |
description | Background: Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities.
Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019.
Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases).
Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important. |
doi_str_mv | 10.1186/s12871-021-01233-9 |
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Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019.
Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases).
Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.</description><identifier>ISSN: 1471-2253</identifier><identifier>EISSN: 1471-2253</identifier><identifier>DOI: 10.1186/s12871-021-01233-9</identifier><identifier>PMID: 33435887</identifier><language>eng</language><publisher>LONDON: Springer Nature</publisher><subject>Abdomen ; Abdominal surgery ; Analysis ; Anesthesia ; Anesthesiology ; Antibiotics ; Asymptomatic ; Cohort analysis ; Cohort Studies ; Complications and side effects ; Coronaviruses ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - surgery ; Demographics ; Epidemics ; Female ; Health system impact ; Heart attacks ; Hospital patients ; Hospitals ; Humans ; Infections ; Kidneys ; Laparoscopy ; Life Sciences & Biomedicine ; Male ; Medical personnel ; Medical research ; Medicine, Experimental ; Middle Aged ; Mortality ; Pandemic ; Pandemics ; Patient Outcome Assessment ; Patient outcomes ; Patients ; Pneumonia ; Postoperative Complications - epidemiology ; Postoperative mortality ; Postoperative outcomes ; Postoperative period ; Pulmonary embolisms ; Quebec - epidemiology ; Science & Technology ; Severe acute respiratory syndrome coronavirus 2 ; Statistical analysis ; Surgery ; Survival Analysis ; Variables ; Ventilators</subject><ispartof>BMC anesthesiology, 2021-01, Vol.21 (1), p.15-15, Article 15</ispartof><rights>COPYRIGHT 2021 BioMed Central Ltd.</rights><rights>2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>28</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000609457300001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c563t-dc5be8c9c30a1cf2c481d0c827f14dc124aeec5cea34d6ce0a732fe1d6b290ae3</citedby><cites>FETCH-LOGICAL-c563t-dc5be8c9c30a1cf2c481d0c827f14dc124aeec5cea34d6ce0a732fe1d6b290ae3</cites><orcidid>0000-0003-0310-0616 ; 0000-0002-9679-7450</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801565/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801565/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2115,27929,27930,39263,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33435887$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carrier, Francois Martin</creatorcontrib><creatorcontrib>Amzallag, Eva</creatorcontrib><creatorcontrib>Lecluyse, Vincent</creatorcontrib><creatorcontrib>Cote, Genevieve</creatorcontrib><creatorcontrib>Couture, Etienne J.</creatorcontrib><creatorcontrib>D'Aragon, Frederick</creatorcontrib><creatorcontrib>Kandelman, Stanislas</creatorcontrib><creatorcontrib>Turgeon, Alexis F.</creatorcontrib><creatorcontrib>Deschamps, Alain</creatorcontrib><creatorcontrib>Nitulescu, Roy</creatorcontrib><creatorcontrib>Djade, Codjo Djignefa</creatorcontrib><creatorcontrib>Girard, Martin</creatorcontrib><creatorcontrib>Beaulieu, Pierre</creatorcontrib><creatorcontrib>Richebe, Philippe</creatorcontrib><title>Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study</title><title>BMC anesthesiology</title><addtitle>BMC ANESTHESIOL</addtitle><addtitle>BMC Anesthesiol</addtitle><description>Background: Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities.
Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019.
Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases).
Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.</description><subject>Abdomen</subject><subject>Abdominal surgery</subject><subject>Analysis</subject><subject>Anesthesia</subject><subject>Anesthesiology</subject><subject>Antibiotics</subject><subject>Asymptomatic</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Complications and side effects</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - surgery</subject><subject>Demographics</subject><subject>Epidemics</subject><subject>Female</subject><subject>Health system impact</subject><subject>Heart attacks</subject><subject>Hospital patients</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infections</subject><subject>Kidneys</subject><subject>Laparoscopy</subject><subject>Life Sciences & Biomedicine</subject><subject>Male</subject><subject>Medical personnel</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Pandemic</subject><subject>Pandemics</subject><subject>Patient Outcome Assessment</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative mortality</subject><subject>Postoperative outcomes</subject><subject>Postoperative period</subject><subject>Pulmonary embolisms</subject><subject>Quebec - epidemiology</subject><subject>Science & Technology</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Survival Analysis</subject><subject>Variables</subject><subject>Ventilators</subject><issn>1471-2253</issn><issn>1471-2253</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNqNkk1v1DAQhiMEoqXwBzigSFyQUIq_EjscKlXL10qV2gNwtbzOeOtVEi-2U9R_z2xTli7igCzL9viZ157RWxQvKTmlVDXvEmVK0oownJRxXrWPimMqMMRYzR8_2B8Vz1LaEEKlIvxpccS54LVS8ri4ugophy1Ek_0NlGHKNgyQSj-WaYprb01fLi6_Lz9UtC23CMGY0_vSlMPUZ2_xBLG04TrEXKY8dbfPiyfO9Ale3K8nxbdPH78uvlQXl5-Xi_OLytYNz1Vn6xUo21pODLWOWaFoR6xi0lHRWcqEAbC1BcNF11ggRnLmgHbNirXEAD8plrNuF8xGb6MfTLzVwXh9FwhxrU3EH_agFeNEKtuBo62QzBlmVkLWirdNLV1Xo9bZrLWdVgN0u6qi6Q9ED29Gf63X4UZjO2nd7ATe3AvE8GOClPXgk4W-NyOEKWkmpBRtgySir_9CN2GKI7ZqRynFakrYH2ptsAA_uoDv2p2oPkeVRraUNkid_oPC0cHgbRjBeYwfJLA5wcaQUgS3r5ESvfOUnj2l0VP6zlO6xaRXD7uzT_ltIgTezsBPWAWXLHrEwh4jhDSkFbXkuCMUafX_9MJn9FwYF2EaM_8F6UHnFA</recordid><startdate>20210112</startdate><enddate>20210112</enddate><creator>Carrier, Francois Martin</creator><creator>Amzallag, Eva</creator><creator>Lecluyse, Vincent</creator><creator>Cote, Genevieve</creator><creator>Couture, Etienne J.</creator><creator>D'Aragon, Frederick</creator><creator>Kandelman, Stanislas</creator><creator>Turgeon, Alexis F.</creator><creator>Deschamps, Alain</creator><creator>Nitulescu, Roy</creator><creator>Djade, Codjo Djignefa</creator><creator>Girard, Martin</creator><creator>Beaulieu, Pierre</creator><creator>Richebe, Philippe</creator><general>Springer Nature</general><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0310-0616</orcidid><orcidid>https://orcid.org/0000-0002-9679-7450</orcidid></search><sort><creationdate>20210112</creationdate><title>Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study</title><author>Carrier, Francois Martin ; Amzallag, Eva ; Lecluyse, Vincent ; Cote, Genevieve ; Couture, Etienne J. ; D'Aragon, Frederick ; Kandelman, Stanislas ; Turgeon, Alexis F. ; Deschamps, Alain ; Nitulescu, Roy ; Djade, Codjo Djignefa ; Girard, Martin ; Beaulieu, Pierre ; Richebe, Philippe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c563t-dc5be8c9c30a1cf2c481d0c827f14dc124aeec5cea34d6ce0a732fe1d6b290ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Abdomen</topic><topic>Abdominal surgery</topic><topic>Analysis</topic><topic>Anesthesia</topic><topic>Anesthesiology</topic><topic>Antibiotics</topic><topic>Asymptomatic</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Complications and side effects</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 - epidemiology</topic><topic>COVID-19 - surgery</topic><topic>Demographics</topic><topic>Epidemics</topic><topic>Female</topic><topic>Health system impact</topic><topic>Heart attacks</topic><topic>Hospital patients</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infections</topic><topic>Kidneys</topic><topic>Laparoscopy</topic><topic>Life Sciences & Biomedicine</topic><topic>Male</topic><topic>Medical personnel</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Pandemic</topic><topic>Pandemics</topic><topic>Patient Outcome Assessment</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Pneumonia</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative mortality</topic><topic>Postoperative outcomes</topic><topic>Postoperative period</topic><topic>Pulmonary embolisms</topic><topic>Quebec - epidemiology</topic><topic>Science & Technology</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Survival Analysis</topic><topic>Variables</topic><topic>Ventilators</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carrier, Francois Martin</creatorcontrib><creatorcontrib>Amzallag, Eva</creatorcontrib><creatorcontrib>Lecluyse, Vincent</creatorcontrib><creatorcontrib>Cote, Genevieve</creatorcontrib><creatorcontrib>Couture, Etienne J.</creatorcontrib><creatorcontrib>D'Aragon, Frederick</creatorcontrib><creatorcontrib>Kandelman, Stanislas</creatorcontrib><creatorcontrib>Turgeon, Alexis F.</creatorcontrib><creatorcontrib>Deschamps, Alain</creatorcontrib><creatorcontrib>Nitulescu, Roy</creatorcontrib><creatorcontrib>Djade, Codjo Djignefa</creatorcontrib><creatorcontrib>Girard, Martin</creatorcontrib><creatorcontrib>Beaulieu, Pierre</creatorcontrib><creatorcontrib>Richebe, Philippe</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMC anesthesiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carrier, Francois Martin</au><au>Amzallag, Eva</au><au>Lecluyse, Vincent</au><au>Cote, Genevieve</au><au>Couture, Etienne J.</au><au>D'Aragon, Frederick</au><au>Kandelman, Stanislas</au><au>Turgeon, Alexis F.</au><au>Deschamps, Alain</au><au>Nitulescu, Roy</au><au>Djade, Codjo Djignefa</au><au>Girard, Martin</au><au>Beaulieu, Pierre</au><au>Richebe, Philippe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study</atitle><jtitle>BMC anesthesiology</jtitle><stitle>BMC ANESTHESIOL</stitle><addtitle>BMC Anesthesiol</addtitle><date>2021-01-12</date><risdate>2021</risdate><volume>21</volume><issue>1</issue><spage>15</spage><epage>15</epage><pages>15-15</pages><artnum>15</artnum><issn>1471-2253</issn><eissn>1471-2253</eissn><abstract>Background: Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities.
Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019.
Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases).
Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.</abstract><cop>LONDON</cop><pub>Springer Nature</pub><pmid>33435887</pmid><doi>10.1186/s12871-021-01233-9</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0310-0616</orcidid><orcidid>https://orcid.org/0000-0002-9679-7450</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Abdomen Abdominal surgery Analysis Anesthesia Anesthesiology Antibiotics Asymptomatic Cohort analysis Cohort Studies Complications and side effects Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - surgery Demographics Epidemics Female Health system impact Heart attacks Hospital patients Hospitals Humans Infections Kidneys Laparoscopy Life Sciences & Biomedicine Male Medical personnel Medical research Medicine, Experimental Middle Aged Mortality Pandemic Pandemics Patient Outcome Assessment Patient outcomes Patients Pneumonia Postoperative Complications - epidemiology Postoperative mortality Postoperative outcomes Postoperative period Pulmonary embolisms Quebec - epidemiology Science & Technology Severe acute respiratory syndrome coronavirus 2 Statistical analysis Surgery Survival Analysis Variables Ventilators |
title | Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study |
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