Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study

Background: Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-1...

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Veröffentlicht in:BMC anesthesiology 2021-01, Vol.21 (1), p.15-15, Article 15
Hauptverfasser: Carrier, Francois Martin, Amzallag, Eva, Lecluyse, Vincent, Cote, Genevieve, Couture, Etienne J., D'Aragon, Frederick, Kandelman, Stanislas, Turgeon, Alexis F., Deschamps, Alain, Nitulescu, Roy, Djade, Codjo Djignefa, Girard, Martin, Beaulieu, Pierre, Richebe, Philippe
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container_issue 1
container_start_page 15
container_title BMC anesthesiology
container_volume 21
creator Carrier, Francois Martin
Amzallag, Eva
Lecluyse, Vincent
Cote, Genevieve
Couture, Etienne J.
D'Aragon, Frederick
Kandelman, Stanislas
Turgeon, Alexis F.
Deschamps, Alain
Nitulescu, Roy
Djade, Codjo Djignefa
Girard, Martin
Beaulieu, Pierre
Richebe, Philippe
description Background: Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019. Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases). Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.
doi_str_mv 10.1186/s12871-021-01233-9
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We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019. Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases). Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.</description><identifier>ISSN: 1471-2253</identifier><identifier>EISSN: 1471-2253</identifier><identifier>DOI: 10.1186/s12871-021-01233-9</identifier><identifier>PMID: 33435887</identifier><language>eng</language><publisher>LONDON: Springer Nature</publisher><subject>Abdomen ; Abdominal surgery ; Analysis ; Anesthesia ; Anesthesiology ; Antibiotics ; Asymptomatic ; Cohort analysis ; Cohort Studies ; Complications and side effects ; Coronaviruses ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - surgery ; Demographics ; Epidemics ; Female ; Health system impact ; Heart attacks ; Hospital patients ; Hospitals ; Humans ; Infections ; Kidneys ; Laparoscopy ; Life Sciences &amp; Biomedicine ; Male ; Medical personnel ; Medical research ; Medicine, Experimental ; Middle Aged ; Mortality ; Pandemic ; Pandemics ; Patient Outcome Assessment ; Patient outcomes ; Patients ; Pneumonia ; Postoperative Complications - epidemiology ; Postoperative mortality ; Postoperative outcomes ; Postoperative period ; Pulmonary embolisms ; Quebec - epidemiology ; Science &amp; Technology ; Severe acute respiratory syndrome coronavirus 2 ; Statistical analysis ; Surgery ; Survival Analysis ; Variables ; Ventilators</subject><ispartof>BMC anesthesiology, 2021-01, Vol.21 (1), p.15-15, Article 15</ispartof><rights>COPYRIGHT 2021 BioMed Central Ltd.</rights><rights>2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019. Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases). Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.</description><subject>Abdomen</subject><subject>Abdominal surgery</subject><subject>Analysis</subject><subject>Anesthesia</subject><subject>Anesthesiology</subject><subject>Antibiotics</subject><subject>Asymptomatic</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Complications and side effects</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - surgery</subject><subject>Demographics</subject><subject>Epidemics</subject><subject>Female</subject><subject>Health system impact</subject><subject>Heart attacks</subject><subject>Hospital patients</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infections</subject><subject>Kidneys</subject><subject>Laparoscopy</subject><subject>Life Sciences &amp; Biomedicine</subject><subject>Male</subject><subject>Medical personnel</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Pandemic</subject><subject>Pandemics</subject><subject>Patient Outcome Assessment</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative mortality</subject><subject>Postoperative outcomes</subject><subject>Postoperative period</subject><subject>Pulmonary embolisms</subject><subject>Quebec - epidemiology</subject><subject>Science &amp; Technology</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Survival Analysis</subject><subject>Variables</subject><subject>Ventilators</subject><issn>1471-2253</issn><issn>1471-2253</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNqNkk1v1DAQhiMEoqXwBzigSFyQUIq_EjscKlXL10qV2gNwtbzOeOtVEi-2U9R_z2xTli7igCzL9viZ157RWxQvKTmlVDXvEmVK0oownJRxXrWPimMqMMRYzR8_2B8Vz1LaEEKlIvxpccS54LVS8ri4ugophy1Ek_0NlGHKNgyQSj-WaYprb01fLi6_Lz9UtC23CMGY0_vSlMPUZ2_xBLG04TrEXKY8dbfPiyfO9Ale3K8nxbdPH78uvlQXl5-Xi_OLytYNz1Vn6xUo21pODLWOWaFoR6xi0lHRWcqEAbC1BcNF11ggRnLmgHbNirXEAD8plrNuF8xGb6MfTLzVwXh9FwhxrU3EH_agFeNEKtuBo62QzBlmVkLWirdNLV1Xo9bZrLWdVgN0u6qi6Q9ED29Gf63X4UZjO2nd7ATe3AvE8GOClPXgk4W-NyOEKWkmpBRtgySir_9CN2GKI7ZqRynFakrYH2ptsAA_uoDv2p2oPkeVRraUNkid_oPC0cHgbRjBeYwfJLA5wcaQUgS3r5ESvfOUnj2l0VP6zlO6xaRXD7uzT_ltIgTezsBPWAWXLHrEwh4jhDSkFbXkuCMUafX_9MJn9FwYF2EaM_8F6UHnFA</recordid><startdate>20210112</startdate><enddate>20210112</enddate><creator>Carrier, Francois Martin</creator><creator>Amzallag, Eva</creator><creator>Lecluyse, Vincent</creator><creator>Cote, Genevieve</creator><creator>Couture, Etienne J.</creator><creator>D'Aragon, Frederick</creator><creator>Kandelman, Stanislas</creator><creator>Turgeon, Alexis F.</creator><creator>Deschamps, Alain</creator><creator>Nitulescu, Roy</creator><creator>Djade, Codjo Djignefa</creator><creator>Girard, Martin</creator><creator>Beaulieu, Pierre</creator><creator>Richebe, Philippe</creator><general>Springer Nature</general><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0310-0616</orcidid><orcidid>https://orcid.org/0000-0002-9679-7450</orcidid></search><sort><creationdate>20210112</creationdate><title>Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study</title><author>Carrier, Francois Martin ; 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We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods: We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Quebec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019. Results: We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases). Conclusion: In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.</abstract><cop>LONDON</cop><pub>Springer Nature</pub><pmid>33435887</pmid><doi>10.1186/s12871-021-01233-9</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0310-0616</orcidid><orcidid>https://orcid.org/0000-0002-9679-7450</orcidid><oa>free_for_read</oa></addata></record>
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subjects Abdomen
Abdominal surgery
Analysis
Anesthesia
Anesthesiology
Antibiotics
Asymptomatic
Cohort analysis
Cohort Studies
Complications and side effects
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - surgery
Demographics
Epidemics
Female
Health system impact
Heart attacks
Hospital patients
Hospitals
Humans
Infections
Kidneys
Laparoscopy
Life Sciences & Biomedicine
Male
Medical personnel
Medical research
Medicine, Experimental
Middle Aged
Mortality
Pandemic
Pandemics
Patient Outcome Assessment
Patient outcomes
Patients
Pneumonia
Postoperative Complications - epidemiology
Postoperative mortality
Postoperative outcomes
Postoperative period
Pulmonary embolisms
Quebec - epidemiology
Science & Technology
Severe acute respiratory syndrome coronavirus 2
Statistical analysis
Surgery
Survival Analysis
Variables
Ventilators
title Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study
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