Effect of oxytocin on lipid accumulation under inflammatory conditions in human macrophages

Oxytocin (OT) is a neuropeptide hormone secreted by the posterior pituitary gland. Deficits in OT action have been observed in patients with behavioral and mood disorders, some of which correlate with an increased risk of cardiovascular disease (CVD). Recent research has revealed a wider systemic ro...

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Veröffentlicht in:	Experimental and molecular pathology 2021-02, Vol.118, p.104604, Article 104604
Hauptverfasser:	Karten, Ariel, Vernice, Nicholas A., Renna, Heather A., Carsons, Steven E., DeLeon, Joshua, Pinkhasov, Aaron, Gomolin, Irving H., Glass, Daniel S., Reiss, Allison B., Kasselman, Lora J.
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCG1 Atherosclerosis Atherosclerosis - chemically induced Atherosclerosis - drug therapy Atherosclerosis - metabolism Atherosclerosis - pathology ATP Binding Cassette Transporter, Subfamily G, Member 1 - metabolism Cardiovascular disease Cells, Cultured Cholesterol - metabolism Cholesterol transport Foam cell formation Foam Cells - drug effects Foam Cells - metabolism Foam Cells - pathology Humans Inflammation Inflammation - chemically induced Inflammation - drug therapy Inflammation - metabolism Inflammation - pathology Life Sciences & Biomedicine Lipopolysaccharides - toxicity Macrophages - drug effects Macrophages - metabolism Macrophages - pathology Oxytocics - pharmacology Oxytocin Oxytocin - pharmacology Pathology Plaque, Atherosclerotic - chemically induced Plaque, Atherosclerotic - drug therapy Plaque, Atherosclerotic - metabolism Plaque, Atherosclerotic - pathology Psychosocial stress Receptors, Oxytocin - metabolism Science & Technology
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