Fingerprinting branches on supercoiled plasmid DNA using quartz nanocapillaries

DNA conformation, in particular its supercoiling, plays an important structural and functional role in gene accessibility as well as in DNA condensation. Enzyme driven changes of DNA plasmids between their linear, circular and supercoiled conformations control the level of condensation and DNA dista...

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Veröffentlicht in:Nanoscale 2021-01, Vol.13 (1), p.32-331
Hauptverfasser: Maheshwaram, Sumanth Kumar, Sreenivasa, Koushik, Soni, Gautam Vivek
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Sprache:eng
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