Safety and immunogenicity of an adjuvanted Escherichia coli adhesin vaccine in healthy women with and without histories of recurrent urinary tract infections: results from a first-in-human phase 1 study

Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide a potential solution to these problems. This study focused on development of an investigational vaccine to prevent...

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Veröffentlicht in:	Human vaccines & immunotherapeutics 2021-05, Vol.17 (5), p.1262-1270
Hauptverfasser:	Eldridge, Gary R., Hughey, Heidi, Rosenberger, Lois, Martin, Steven M., Shapiro, Andrew Marc, D'Antonio, Elizabeth, Krejci, Kent G., Shore, Neal, Peterson, James, Lukes, Andrea S., Starks, Courtney M.
Format:	Artikel
Sprache:	eng
Schlagworte:	FimH phase 1 Research Paper TLR4 agonist Urinary tract infection vaccine
Online-Zugang:	Volltext
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