Temporal evolution of cardiac mitochondrial dysfunction in a type 1 diabetes model. Mitochondrial complex I impairment, and H 2 O 2 and NO productions as early subcellular events

The aim of this work was to study the early events that occur in heart mitochondria and to analyse the temporal evolution of cardiac mitochondrial dysfunction in a type 1 diabetes model. Male Wistar rats were injected with Streptozotocin (STZ, single dose, 60 mg × kg , i.p.) and hyperglycemic state...

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Veröffentlicht in:Free radical biology & medicine 2021-01, Vol.162, p.129
Hauptverfasser: Rukavina-Mikusic, Ivana A, Rey, Micaela, Martinefski, Manuela, Tripodi, Valeria, Valdez, Laura B
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Sprache:eng
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