Transient NADPH oxidase 2-dependent H 2 O 2 production drives early palmitate-induced lipotoxicity in pancreatic islets

Modern lifestyles, including lack of physical activity and poor nutritional habits, are driving the rapidly increasing prevalence of obesity and type 2 diabetes. Increased levels of free fatty acids (FFAs), particularly saturated FFAs, in obese individuals have been linked to pancreatic β-cell failu...

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Veröffentlicht in:	Free radical biology & medicine 2021-01, Vol.162, p.1
Hauptverfasser:	Vilas-Boas, Eloisa Aparecida, Nalbach, Lisa, Ampofo, Emmanuel, Lucena, Camila Ferraz, Naudet, Léa, Ortis, Fernanda, Carpinelli, Angelo Rafael, Morgan, Bruce, Roma, Leticia Prates
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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