The Impact of Immunosuppression and Autoimmune Disease on Severe Outcomes in Patients Hospitalized with COVID-19

Immunosuppression (IS) and autoimmune disease (AD) are prevalent in patients with severe coronavirus disease 2019 (COVID-19), but their impact on its clinical course is unknown. We investigated relationships between IS, AD, and outcomes in patients hospitalized with COVID-19. Data on consecutive adm...

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Veröffentlicht in:	Journal of clinical immunology 2021-02, Vol.41 (2), p.315-323
Hauptverfasser:	Monreal, Enric, Sainz de la Maza, Susana, Fernández-Velasco, Jose Ignacio, Natera-Villalba, Elena, Rita, Claudia Geraldine, Rodríguez-Jorge, Fernando, Beltrán-Corbellini, Álvaro, Iturrieta-Zuazo, Ignacio, Rodríguez de Santiago, Enrique, Espiño, Mercedes, de Andrés, Ana, Fortún, Jesús, Barbero, Esther, Vázquez, Mónica, Fernández Lucas, Milagros, Manzano, Luis, Montero-Errasquín, Beatriz, Costa-Frossard, Lucienne, Masjuan, Jaime, Villar, Luisa María
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Autoimmune diseases Autoimmune Diseases - complications Autoimmune Diseases - epidemiology Autoimmune Diseases - metabolism Autoimmune Diseases - therapy Biomarkers Biomedical and Life Sciences Biomedicine Combined Modality Therapy Comorbidity Coronaviruses COVID-19 COVID-19 - complications COVID-19 - diagnosis COVID-19 - epidemiology COVID-19 - metabolism Cytokines - metabolism Death Female Health Impact Assessment Hospitalization Humans Immunology Immunosuppression Immunosuppression - adverse effects Immunosuppression - methods Infectious Diseases Interleukin 6 Internal Medicine Kaplan-Meier Estimate Life Sciences & Biomedicine Male Mechanical ventilation Medical Microbiology Medical records Middle Aged NAD Original Original Article Patients Prognosis Respiratory distress syndrome Retrospective Studies SARS-CoV-2 Science & Technology Serum levels Trauma Severity Indices Treatment Outcome
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