Pharmacokinetics, safety and metabolite profiling of minesapride, a novel 5-HT 4 receptor partial agonist, in healthy elderly and young subjects

Minesapride is a novel 5-hydroxytryptamine 4 (5-HT ) receptor partial agonist that is expected to show efficacy in patients with irritable bowel syndrome with predominant constipation and functional constipation. An open-label study was conducted to evaluate pharmacokinetics (PK) and safety of mines...

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Veröffentlicht in:	Drug metabolism and pharmacokinetics 2020-12, Vol.35 (6), p.563
Hauptverfasser:	Hamatani, Tatsuto, Shibue, Yuta, Sawada, Naoyuki, Takagaki, Takeshi, Hashimoto, Masayo, Nakada, Yosuke, Kakuyama, Hiroyoshi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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